Malignant melanoma of the vulva: a clinicopathological study of 50 women
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1990.tb01737.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 97, Issue 2, pages 124–133, February 1990
Additional Information
How to Cite
BRADGATE, M. G., ROLLASON, T. P., McCONKEY, C. C. and POWELL, J. (1990), Malignant melanoma of the vulva: a clinicopathological study of 50 women. BJOG: An International Journal of Obstetrics & Gynaecology, 97: 124–133. doi: 10.1111/j.1471-0528.1990.tb01737.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 31 March 1989 Accepted 6 September 1989
- Abstract
- References
- Cited By
Summary. A clinicopathological review of 50 primary malignant melanomas of the vulva in the West Midlands region of England is presented. The overall 5-year-survival rate was 35%, when adjusted for age. Significant predictors of survival were clinical stage, patient age, tumour ulceration, cell type and mitotic rate. Tumour thickness was of prognostic importance but as a prognostic variable it did not operate independently of stage and as most lesions were deeply invasive at presentation vulval tumours must be separated for prognostic purposes into bands at greater overall thicknesses than those used for skin melanomas generally. There was no significant relation between survival and type of surgery performed as a primary therapeutic procedure.

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