Reduced atrial natriuretic peptide concentrations in premenstrual syndrome
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1990.tb01825.x
Issue
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BJOG: An International Journal of Obstetrics & Gynaecology
Volume 97, Issue 5, pages 397–401, May 1990
Additional Information
How to Cite
HUSSAIN, S. Y., O'BRIEN, P. M. S., DE SOUZA, V., OKONOFUA, F. and DANDONA, P. (1990), Reduced atrial natriuretic peptide concentrations in premenstrual syndrome. BJOG: An International Journal of Obstetrics & Gynaecology, 97: 397–401. doi: 10.1111/j.1471-0528.1990.tb01825.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 26 July 1989; Accepted 22 October 1989
- Abstract
- References
- Cited By
Summary. Atrial natriuretic peptide (ANP) concentrations were determined by radioimmunoassay technique in 23 women, 11 women with premenstrual syndrome (PMS) and 12 comparable asymptomatic women. The asymptomatic women showed no change in ANP concentration during the menstrual cycle. In the PMS group ANP levels showed a significant fall in the midluteal phase compared to levels in the follicular phase. Throughout the cycle ANP concentrations were lower in the PMS group than in the comparison group. This difference was statistically significant in the early, mid and late luteal phases of the cycle. The lower ANP concentration in the PMS group in the luteal phases may indicate either a lower plasma volume or a decrease in the total body sodium content or both. These findings are contrary to those expected.

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