Uterine artery Doppler in the investigatioin of pregnancies with raised maternal serum alphafetoprotein
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1990.tb01831.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b)
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 97, Issue 5, pages 431–435, May 1990
Additional Information
How to Cite
ARISTIDOU, A., VAN DEN HOF, M. C., CAMPBELL, S. and NICOLAIDES, K. (1990), Uterine artery Doppler in the investigatioin of pregnancies with raised maternal serum alphafetoprotein. BJOG: An International Journal of Obstetrics & Gynaecology, 97: 431–435. doi: 10.1111/j.1471-0528.1990.tb01831.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 15 May 1989; Accepted 28 September 1989
- Abstract
- References
- Cited By
Summary. Uterine artery flow velocity waveforms (FVW) were obtained prospectively by continuous wave Doppler at 18–22 weeks gestation from 98 women with an unexplained elevation in maternal serum alpha-fetoprotein (MSAFP). A notch in either the left or right uterine artery FVW was present in 18 pregnancies of which seven resulted in perinatal death and six in the birth of very immature and/or severely growth retarded babies. Conversely, in 66 of 80 pregnancies the absence of a notch was associated with the livebirth of an infant beyond 32 weeks gestation, with a birthweight above the 5th centile. It is suggested that the presence of a notch in the uterine artery FVW is a good predictor of poor perinatal outcome.

1471-0528/asset/BJO_left.gif?v=1&s=0fb87361cdb6be25fdf05019eed6d47f5143f610)
1471-0528/asset/olbannerright.gif?v=1&s=3892ef16ff18d6834c302faf85268a49f5fc588f)