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A morphological and immunological study of human placental bed biopsies in miscarriage
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1990.tb02468.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 97, Issue 11, pages 984–988, November 1990
Additional Information
How to Cite
MICHEL, M. Z., KHONG, T. Y., CLARK, D. A. and BEARD, R. W. (1990), A morphological and immunological study of human placental bed biopsies in miscarriage. BJOG: An International Journal of Obstetrics & Gynaecology, 97: 984–988. doi: 10.1111/j.1471-0528.1990.tb02468.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 16 November 1989 Accepted25 May 1990
- Abstract
- References
- Cited By
Summary. Placental bed biopsies were examined in thrce groups of pregnant women for maternal vascular response to placentation as well as for the presence of cells associated with local immunosuppression activity. In the group of women undergoing legal abortion, the histological appearance of trophoblastic invasion was normal in all but one, and the proportion of immunosuppressor cells was also normal. In the missed miscarriage group the histological appearances were abnormal except in one patient. In women with a history of recurrent miscarriage who had miscarried after immunization, placentation was normal in some and defective in others. Immunosuppressor cells appeared to be diminished in number, although there was no correlation between the cytotoxic status of their sera and their pregnancy outcome.