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The rate of rise of corticotrophin releasing factor and endogenous digoxin-like immunoreactivity in normal and abnormal pregnancy
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1990.tb02579.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 97, Issue 9, pages 832–837, September 1990
Additional Information
How to Cite
WOLFE, C. D. A., PETRUCKEVITCH, A., QUARTERO, R., CARABELLI, P., POSTON, L., KERKEZ, S., CAMPBELL, E., LOWRY, P. J. and LINTON, E. A. (1990), The rate of rise of corticotrophin releasing factor and endogenous digoxin-like immunoreactivity in normal and abnormal pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 97: 832–837. doi: 10.1111/j.1471-0528.1990.tb02579.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 14 November 1989 Accepted 20 May 1990
- Abstract
- References
- Cited By
Summary. Maternal plasma concentrations of corticotrophin releasing factor (CRF) and endogenous digoxin-like immunoreactivity (EDLI) were estimated in 80 normal and 88 abnormal pregnancies which were sampled sequentially from 24 weeks gestation to delivery. A slope was fitted for each woman's antenatal EDLI and CRF values, both of which rose significantly during gestation, and the mean of the slopes for the normal and abnormal groups for each value compared. There was no evidence of significant mean differences between groups for EDLI but there was evidence of a significant mean difference for CRF (P<0.05). After adjustment for other variables which may affect pregnancy outcome, the slopes for CRF were found not to be significantly related to outcome.