Cervical carcinoma in the Grampian region (1980–1991): a population-based study of survival and cervical cytology history
Article first published online: 19 AUG 2005
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 101, Issue 9, pages 797–803, September 1994
How to Cite
Macleod, A., Kitchener, H. C., Parkin, D. E., Sarkar, T., Miller, I. D., Mann, E., Gordon, N. and Campbell, M. (1994), Cervical carcinoma in the Grampian region (1980–1991): a population-based study of survival and cervical cytology history. BJOG: An International Journal of Obstetrics & Gynaecology, 101: 797–803. doi: 10.1111/j.1471-0528.1994.tb11949.x
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 25 August 1993, Accepted 13 April 1994
Objectives To study survival in women treated for cervical carcinoma in Grampian region, to identify clinical and pathological prognostic factors, and to correlate survival with cytology history.
Design A retrospective study of all cases of cervical carcinoma using a prospectively gathered database. Data validated by 1 in 10 randomised retrospective case note sampling.
Setting Aberdeen Royal Infirmary.
Subjects Three hundred and sixty-three women resident within Grampian diagnosed as having cervical carcinoma between 1980 and 1991, with five-year survival data on the 206 diagnosed by the end of 1986.
Main outcome measure Five-year survival rates.
Results The mean annual incidence of cervical carcinoma in our population was 11.2 per 100 000 women, with an overall five-year survival of 67% in those under 40 years of age and 60% in those aged 40 years and over. On univariate analysis, survival was significantly adversely affected by tumour stage, grade and absence of previous smears. On multivariate analysis, the effect of previous smear history was lost, but stage and grade remained strong independent risk factors for survival. There was no significant difference in five-year survival by age or tumour type.
Conclusions The prognosis of cervical carcinoma in Grampian region was independently affected only by stage of disease and tumour grading and cervical smear history.