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Selenium deficiency and miscarriage: a possible link?
Article first published online: 19 AUG 2005
DOI: 10.1111/j.1471-0528.1996.tb09663.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 103, Issue 2, pages 130–132, February 1996
Additional Information
How to Cite
Barrington, J. W., Lindsay, P., James, D., Smith, S. and Roberts, A. (1996), Selenium deficiency and miscarriage: a possible link?. BJOG: An International Journal of Obstetrics & Gynaecology, 103: 130–132. doi: 10.1111/j.1471-0528.1996.tb09663.x
Publication History
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 10 February 1995 Accepted 15 August 1995
- Abstract
- Article
- References
- Cited By
Objective To investigate a possible relationship between a deficiency in serum selenium concentration and first trimester miscarriage.
Design An observational study.
Setting A teaching hospital in South Wales.
Participants and methods Serum selenium, albumin and total protein concentration were measured in 40 women admitted with first trimester nonrecurrent miscarriage. The results were compared with an equal number of age-matched nonpregnant healthy volunteers, and also from 40 pregnant women attending the antenatal clinic for booking in the first trimester.
Results A reduction in serum selenium normally occurs in the first trimester of pregnancies that progress to term. However, a further statistically highly significant decrease in serum selenium was observed in those women who miscarried.
Conclusion Further studies are required to assess the potential benefits of selenium supplements.