The Kleihauer Technique: an accurate method of quantifying fetomaternal haemorrhage?
Article first published online: 19 AUG 2005
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 104, Issue 7, pages 845–846, July 1997
How to Cite
Duckett, J. R. A. and Constantine, G. (1997), The Kleihauer Technique: an accurate method of quantifying fetomaternal haemorrhage?. BJOG: An International Journal of Obstetrics & Gynaecology, 104: 845–846. doi: 10.1111/j.1471-0528.1997.tb12032.x
- Issue published online: 19 AUG 2005
- Article first published online: 19 AUG 2005
- Received 14 May 1996 Accepted 8 August 1996
Blood was taken from 100 consecutive asymptomatic women at 17 to 18 weeks of pregnancy for Kleihauer testing. When a proportion of these slides were assessed at a different hospital there was agreement in only 46%. When the number of fetal cells were quantified there were differences of over 500%. These results show a large niter-observer and inter-hospital variation in interpreting Kleihauer slides. If these investigations are to be performed, it is essential that clinicians can rely on the results. There is a need for quality control measures and audit so that laboratories can rectify any deficiencies in their techniques.