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Maternal plasma glucose at high altitude
Article first published online: 22 DEC 2003
DOI: 10.1111/j.1471-0528.2001.00072.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 108, Issue 3, pages 254–257, March 2001
Additional Information
How to Cite
Krampl, E., Kametas, N. A., Zegarra, A. M. C., Roden, M. and Nicolaides, K. H. (2001), Maternal plasma glucose at high altitude. BJOG: An International Journal of Obstetrics & Gynaecology, 108: 254–257. doi: 10.1111/j.1471-0528.2001.00072.x
Publication History
- Issue published online: 22 DEC 2003
- Article first published online: 22 DEC 2003
- Accepted 1 November 2000
- Abstract
- Article
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Objective To compare plasma glucose in pregnant women living at very high altitude; pregnant women living at sea level; non-pregnant women living at very high altitude; and non-pregnant women living at sea level.
Design sectional study.
Participants Ninety-four pregnant women attending for routine antenatal care at 8–42 weeks of gestation in Cerro de Pasco, Peru which is situated 4370 m above sea level; 122 pregnant women in Lima, which is at sea level; 22 non-pregnant women in Cerro de Pasco; and 31 non-pregnant women in Lima.
Methods Plasma glucose concentrations were measured in samples obtained from the antecubital vein between 8 am and 10 am after an overnight period of fasting for at least 10 hours.
Results Fasting plasma glucose was lower in women at high altitude than in those at sea level, and in both groups the level was lower in pregnant women than in non-pregnant controls. The body mass index was not significantly different between all four groups, and it did not have a significant independent contribution in explaining the variance in fasting plasma glucose.
Conclusion Women native at high altitude have lower plasma glucose concentrations before and during pregnancy than those at sea level.