1471-0528/asset/BJO_left.gif?v=1&s=0fb87361cdb6be25fdf05019eed6d47f5143f610)
1471-0528/asset/olbannerright.gif?v=1&s=3892ef16ff18d6834c302faf85268a49f5fc588f)
A randomised placebo-controlled trial to determine the effect of vitamin E in treatment of primary dysmenorrhoea
Article first published online: 28 JUN 2008
DOI: 10.1111/j.1471-0528.2003.00279.x
Issue
1471-0528/asset/cover.gif?v=1&s=b4e1d96c46e18c61210d584b63c13ee375cf562b "BJOG: An International Journal of Obstetrics & Gynaecology")
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 108, Issue 11, pages 1181–1183, November 2001
Additional Information
How to Cite
Ziaei, S., Faghihzadeh, S., Sohrabvand, F., Lamyian, M. and Emamgholy, T. (2001), A randomised placebo-controlled trial to determine the effect of vitamin E in treatment of primary dysmenorrhoea. BJOG: An International Journal of Obstetrics & Gynaecology, 108: 1181–1183. doi: 10.1111/j.1471-0528.2003.00279.x
Publication History
- Issue published online: 28 JUN 2008
- Article first published online: 28 JUN 2008
- Accepted 13 May 2001
- Abstract
- Article
- References
- Cited By
Objective To determine whether vitamin E is effective in the treatment of primary dysmenorrhoea.
Design A randomised placebo-controlled trial.
Participants One hundred girls, aged 16–18 years old who suffered from primary dysmenorrhoea, among 1000 students attending a public high school in Region 5 in the Greater Tehran Municipality.
Methods Fifty girls were given 500 units of vitamin E (five tablets) per day, and 50 were given five placebo tablets per day. The treatment began two days before the beginning of menstruation and continued through the first three days of bleeding. The severity of pain before and after the treatment was studied. Treatment in both groups was carried out in two consecutive menstrual periods.
Results The severity of pain in the two groups was reduced after treatment, but the reduction was greater in the group treated with vitamin E. These differences were maintained in the second month of therapy.
Conclusion Both placebo and vitamin E are effective in relieving symptoms due to primary dysmenorrhoea, but the effects of vitamin E are more marked.