• 1
    Hawkins JL, Beaty BR. Update on obstetric anaesthesia practices in the US. Anesthesiology 1999;91: A1060.
  • 2
    Wilson CM, McClean E, Moore J, Dundee JW. A double-blind comparison of intramuscular pethidine and nalbuphine in labour. Anesthesia 1986;41: 12071213.
  • 3
    Morrison CE, Dutton D, Howie H, Gilmour H. Pethidine compared with meptazinol during labour. A prospective randomized double-blind study in 1100 patients. Anesthesia 1987;42: 714.
  • 4
    Fairlie FM, Marshall L, Walker JJ, Elbourne D. Intramuscular opioids for maternal pain relief in labour: a randomized controlled trial comparing pethidine with diamorphine. Br J Obstet Gynaecol 1999;106: 11811187.
  • 5
    Olofsson CH, Ekblom A, Ekman-Ordeberg G, Hjelm A, Irestedt L. Lack of analgesic effect of systemically administered morphine or pethidine on labour pain. Br J Obstet Gynaecol 1996;103: 968972.
  • 6
    Reynolds F, Crowhurst JA. Opioids in labour—no analgesic effect. Lancet 1997;349: 45.
  • 7
    Aly EE, Shilling RS. Are we willing to change? Anesthesia 2000;55: 419420.
  • 8
    Bricker L, Lavender T. Parental opioids for labour pain relief: a systematic review. Am J Obstet Gynecol 2002;186: S94S109.
  • 9
    Douglas MJ, Levinson G. Systemic medication for labour and delivery. In: HughesSC, LevinsonG, RosenMA, editors. Anesthesia for Obstetrics, 4th edition. Philadelphia: Lippincott Williams and Wilkins, 2001: 105121.
  • 10
    Gaylard DG, Carson RJ, Reynolds F. Effect of umbilical perfusate pH and controlled maternal hypotension on placental drug transfer in the rabbit. Anesth Analg 1990;71: 4248.
  • 11
    Belsey EM, Rosenblatt DB, Lieberman BA, et al. The influence of maternal analgesia on neonatal behaviour: I. Pethidine. Br J Obstet Gynaecol 1981;88: 398406.
  • 12
    Belfrage P, Boreus LO, Hartvig P, Irestedt L, Raabe N. Neonatal depression after obstetrical analgesia with pethidine. The role of the injection-delivery time interval and of the plasma concentrations of pethidine and norpethidine. Acta Obstet Gynecol Scand 1981;60: 4349.
  • 13
    Nissen E, Widstrom AM, Lilja G, et al. Effects of routinely given pethidine during labour on infants' developing breastfeeding behaviour. Effects of dose-delivery time interval and various concentrations of pethidine/norpethidine in cord plasma. Acta Paediatr 1997;86: 201208.
  • 14
    Chan K, Kendall MJ, Mitchard M. A quantitative gas–liquid chromatographic method for the determination of pethidine and its metabolites, norpethidine and pethidine N-oxide in human biological fluids. J Chromatogr 1974;89: 169176.
  • 15
    Chan K, Lau OW, Wong YC. Determination of pethidine and its major metabolites in human urine by gas chromatography. J Chromatogr 1991;565: 247254.
  • 16
    Lee BB, Ngan Kee WD, Hung VYS, Wong ELY. Combined spinal–epidural analgesia in labour: comparison of two doses of intrathecal bupivacaine with fentanyl. Br J Anaesth 1999;83: 868871.
  • 17
    Todd KH, Funk KG, Funk JP, Bonacci R. Clinical significance of reported changes in pain severity. Ann Emerg Med 1996;27: 485489.
  • 18
    Pocock SJ. Clinical Trials. A Practical Approach. Chichester: Wiley, 1983.
  • 19
    Austin KL, Stapleton JV, Mather LE. Relationship between blood pethidine concentrations and analgesic response: a preliminary report. Anesthesiology 1980;53: 460466.
  • 20
    Polley LS, Columb MO, Naughton NN, Wagner DS, van de Ven CJ. Relative analgesic potencies of ropivacaine and bupivacaine for epidural analgesia in labour: implications for therapeutic indexes. Anesthesiology 1999;90: 944950.
  • 21
    Camann W, Abouleish A, Eisenach J, Hood D, Datta S. Intrathecal sufentanil and epidural bupivacaine for labour analgesia: dose–response of individual agents and in combination. Reg Anesth Pain Med 1998;23: 457462.
  • 22
    Ramin SM, Gambling DR, Lucas MJ, Sharma SK, Sidawi JE, Leveno KJ. Randomized trial of epidural versus intravenous analgesia during labour. Obstet Gynecol 1995;86: 783789.
  • 23
    Sharma SK, Sidawi JE, Ramin SM, Lucas MJ, Leveno KJ, Cunningham FG. Cesarean delivery. A randomized trial of epidural versus patient-controlled pethidine analgesia during labour. Anesthesiology 1997;87: 487494.
  • 24
    Vella L, Francis D, Houlton P, Reynolds F. Comparison of the antiemetics metoclopramide and promethazine in labour. Br Med J (Clin Res Ed) 1985;290: 11731175.
  • 25
    Husemeyer RP, Cummings AJ, Rosankiewicz JR, Davenport HT. A study of pethidine kinetics and analgesia in women in labour following intravenous, intramuscular and epidural administration. Br J Clin Pharmacol 1982;13: 171176.
  • 26
    Houghton IT, Aun CST, Gin T, Lau JTF. Inter-ethnic differences in postoperative pethidine requirements. Anaesth Intensive Care 1992;20: 5255.
  • 27
    Cammu H, Verlaenen H, Amy JJ, De Koster K, Derde MP, Buekens P. Epidural analgesia in active management of labour. Acta Obstet Gynecol Scand 1994;73: 235239.