The fetal sex ratio and metabolic, biochemical, haematological and clinical indicators of severity of hyperemesis gravidarum
Article first published online: 18 MAY 2006
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 113, Issue 6, pages 733–737, June 2006
How to Cite
Tan, P., Jacob, R., Quek, K. and Omar, S. (2006), The fetal sex ratio and metabolic, biochemical, haematological and clinical indicators of severity of hyperemesis gravidarum. BJOG: An International Journal of Obstetrics & Gynaecology, 113: 733–737. doi: 10.1111/j.1471-0528.2006.00947.x
- Issue published online: 18 MAY 2006
- Article first published online: 18 MAY 2006
- Accepted 7 March 2006.
- Fetal sex;
- hyperemesis gravidarum;
The association between female fetal sex and hyperemesis gravidarum is well established in European and North American populations. The association between female fetuses and severity of hyperemesis remains uncertain. A retrospective study based on case notes review of 166 Asian women hospitalised for hyperemesis was performed. Female fetuses were significantly associated with hyperemesis in our population (P= 0.004, OR 1.6, 95% CI 1.2–2.2) as well as associated with severe ketonuria and high urea. When both severe ketonuria and high urea were present at initial hospital admission for hyperemesis, 83% (95% CI 66–93) of the fetuses were female.