Fasting capillary glucose as a screening test for gestational diabetes mellitus
Article first published online: 25 AUG 2006
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 113, Issue 9, pages 1067–1071, September 2006
How to Cite
Fadl, H., Östlund, I., Nilsson, K. and Hanson, U. (2006), Fasting capillary glucose as a screening test for gestational diabetes mellitus. BJOG: An International Journal of Obstetrics & Gynaecology, 113: 1067–1071. doi: 10.1111/j.1471-0528.2006.01032.x
- Issue published online: 25 AUG 2006
- Article first published online: 25 AUG 2006
- Accepted 12 June 2006.
- Fasting capillary glucose;
- gestational diabetes mellitus;
Objective To evaluate fasting capillary glucose as a screening test for gestational diabetes mellitus (GDM) compared with traditional risk factors and repeated random capillary glucose measurements.
Design Cross-sectional, population-based study.
Setting Maternal Health Care Clinics in Örebro County, Sweden.
Population An unselected population of women without diabetes.
Methods Fasting capillary glucose levels were measured at gestational weeks 28–32. Random capillary glucose levels were measured four to six times during pregnancy. Traditional risk factors for GDM were registered. GDM was diagnosed using a 75-g oral glucose tolerance test.
Main outcome measures Sensitivity, specificity, likelihood ratios.
Results In 55 of 3616 women participating in the study, GDM was diagnosed before 34 weeks of gestation. For fasting capillary glucose cutoff values between 4.0 and 5.0 mmol/l, sensitivity was in the range between 87 and 47% and specificity between 51 and 96%. Using a combined screening model of traditional risk factors with fasting capillary glucose at various cutoff values increased the sensitivity only slightly compared with using fasting capillary glucose alone.
Conclusion In this Swedish, unselected, low-risk population, fasting capillary glucose measurements were found to be an acceptable and useful screening test for GDM.