Polycystic ovary syndrome and pregnancy outcome: red herring or red flag?
Article first published online: 11 JUL 2007
RCOG 2007 BJOG An International Journal of Obstetrics and Gynaecology
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 114, Issue 8, pages 922–932, August 2007
How to Cite
Siassakos, D. and Wardle, P. (2007), Polycystic ovary syndrome and pregnancy outcome: red herring or red flag?. BJOG: An International Journal of Obstetrics & Gynaecology, 114: 922–932. doi: 10.1111/j.1471-0528.2007.01418.x
- Issue published online: 11 JUL 2007
- Article first published online: 11 JUL 2007
- Accepted 9 May 2007.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women, associated with a characteristic ovarian appearance at ultrasound scan, hyperandrogenism, and ovulatory disorders. The pathogenesis appears to be mainly related to reduced insulin sensitivity in peripheral tissues, leading to hyperinsulinaemia. There is a wide variation in the severity of PCOS symptoms. Women with PCOS are believed to be predisposed to a variety of complications in pregnancy. We present a summary of the evidence surrounding these claims and discuss the weaknesses of the available to date studies.