A randomised trial comparing the H Pipelle with the standard Pipelle for endometrial sampling at ‘no-touch’ (vaginoscopic) hysteroscopy
Article first published online: 12 DEC 2008
© 2008 Authors Journal compilation © RCOG 2008 BJOG An International Journal of Obstetrics and Gynaecology
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 116, Issue 1, pages 32–37, January 2009
How to Cite
Madari, S., Al-Shabibi, N., Papalampros, P., Papadimitriou, A. and Magos, A. (2009), A randomised trial comparing the H Pipelle with the standard Pipelle for endometrial sampling at ‘no-touch’ (vaginoscopic) hysteroscopy. BJOG: An International Journal of Obstetrics & Gynaecology, 116: 32–37. doi: 10.1111/j.1471-0528.2008.01992.x
- Issue published online: 12 DEC 2008
- Article first published online: 12 DEC 2008
- Accepted 16 September 2008.
- Endometrial biopsy;
- H Pipelle;
- ‘no-touch’ hysteroscopy;
- Pipelle de Cornier;
- vaginoscopic hysteroscopy
Objectives To evaluate the effectiveness and tolerance of H Pipelle compared with the standard Pipelle as an endometrial biopsy device at outpatient ‘no-touch’ hysteroscopy.
Design A prospective randomised trial carried out in an outpatient diagnostic hysteroscopy clinic.
Setting A large undergraduate teaching hospital.
Population Sixty women investigated for abnormal menstruation in an outpatient diagnostic hysteroscopy clinic.
Methods Prospective randomised trial comparing the H Pipelle with the standard Pipelle de Cornier.
Main outcome measures Adequacy of the biopsy specimens and women’s experience.
Results Ninety-three percent (H Pipelle) and 87% (Pipelle) of the biopsy specimens were judged to be adequate for histological diagnosis (P > 0.05). However, obtaining endometrial sampling with the H Pipelle was significantly quicker (median times: 39 seconds [H Pipelle] and 102 seconds [Pipelle], P < 0.0001) and less painful (median visual analogue scale score: 1 [H Pipelle] and 5 [Pipelle], P = 0.011).
Conclusions The H Pipelle not only makes it possible to perform hysteroscopy and endometrial biopsy with minimal instrumentation but is also associated with a shorter biopsy time and less discomfort than the standard Pipelle without any loss of biopsy adequacy.