Epidemiology

You have full text access to this OnlineOpen article

Effect of Swedish snuff (snus) on preterm birth

  1. A-K Wikström1,2,
  2. S Cnattingius1,
  3. MR Galanti3,
  4. H Kieler1,
  5. O Stephansson1,4

Article first published online: 11 MAY 2010

DOI: 10.1111/j.1471-0528.2010.02575.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 117, Issue 8, pages 1005–1010, July 2010

Additional Information

How to Cite

Wikström, A.-K., Cnattingius, S., Galanti, M., Kieler, H. and Stephansson, O. (2010), Effect of Swedish snuff (snus) on preterm birth. BJOG: An International Journal of Obstetrics & Gynaecology, 117: 1005–1010. doi: 10.1111/j.1471-0528.2010.02575.x

Author Information

  1. 1

    Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden

  2. 2

    Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden

  3. 3

    Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden

  4. 4

    Department of Woman and Child Health, Division of Obstetrics and Gynecology, Karolinska University Hospital and Institute, Stockholm, Sweden

*Dr A-K Wikström, Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden. Email anna-karin.wikstrom@kbh.uu.se

Publication History

  1. Issue published online: 8 JUN 2010
  2. Article first published online: 11 MAY 2010
  3. Accepted 23 March 2010. Published Online 11 May 2010.

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (86K)

Keywords:

  • Pregnancy;
  • premature birth;
  • smokeless;
  • snuff;
  • tobacco

Please cite this paper as: Wikström A-K, Cnattingius S, Galanti M, Kieler H, Stephansson O. Effect of Swedish snuff (snus) on preterm birth. BJOG 2010;117:1005–1010.

Objective  To compare the effects of Swedish snuff and cigarette smoking on risks of preterm birth.

Design  Population-based cohort study.

Setting  Sweden.

Population  All live, singleton births in Sweden 1999–2006.

Methods  Odds ratios (OR) with 95% confidence intervals (CI) were used to estimate relative risks for preterm birth in snuff users (n = 7607), light smokers (1–9 cigarettes/day; n = 41 436) and heavy smokers (ten or more cigarettes/day; n = 16 951) using non-tobacco users (n = 503 957) as reference.

Main outcome measures  Very (<32 weeks) and moderately (32–36 weeks) preterm birth.

Results  Compared with non-tobacco users, snuff users had increased risks of both very (adjusted OR 1.38; 95% CI 1.04–1.83) and moderately (adjusted OR 1.25; 95% CI 1.12–1.40) preterm birth. Compared with non-tobacco users, light smokers had increased risks of both very (adjusted OR 1.60; 95% CI 1.42–1.81) and moderately (adjusted OR: 1.18; 95% CI: 1.12–1.24) preterm birth, and heavy smokers had even higher risks. Among smokers, but not among snuff users, the risk was more pronounced for spontaneous than induced preterm birth.

Conclusions  The use of Swedish snuff was associated with increased risks of very and moderately preterm birth with both spontaneous and induced onsets. Swedish snuff is not a safe alternative to cigarette smoking during pregnancy.

View Full Article (HTML) Get PDF (86K)