Smoking and pregnancy-related pelvic pain
Article first published online: 26 MAY 2010
© 2010 The Authors Journal compilation © RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology
BJOG: An International Journal of Obstetrics & Gynaecology
Volume 117, Issue 8, pages 1019–1026, July 2010
How to Cite
Biering, K., Aagaard Nohr, E., Olsen, J., Hjollund, N., Nybo Andersen, A.-M. and Juhl, M. (2010), Smoking and pregnancy-related pelvic pain. BJOG: An International Journal of Obstetrics & Gynaecology, 117: 1019–1026. doi: 10.1111/j.1471-0528.2010.02591.x
- Issue published online: 8 JUN 2010
- Article first published online: 26 MAY 2010
- Accepted 7 April 2010. Published Online 26 May 2010.
- pelvic pain;
- risk factors;
Please cite this paper as: Biering K, Aagaard Nohr E, Olsen J, Hjollund N, Nybo Andersen A-M, Juhl M. Smoking and pregnancy-related pelvic pain. BJOG 2010;117:1019–1026.
Objective To investigate possible associations between smoking and pregnancy-related pelvic pain.
Design Nested case–control study.
Setting Denmark 2000–2001.
Population The Danish National Birth Cohort.
Methods The women were interviewed twice in pregnancy and twice after childbirth. The first pregnancy interview provided information on smoking and possible confounding factors, whereas the first interview after birth addressed case identification. Cases (n = 2302) were defined on the basis of self-reported pelvic pain, and controls were selected among women who did not report pelvic pain (n = 2692). Logistic regression analysis was used to estimate associations between smoking and pelvic pain.
Main outcome mreasue Pregnancy-related pelvic pain.
Results Compared with non-smokers, women who smoked during pregnancy had an adjusted odds ratio of 1.2 (1.0–1.4) for overall pelvic pain, similar to women who stopped smoking in early pregnancy 1.3 (1.1–1.7). The equivalent adjusted odds ratio for severe pelvic pain was 1.2 (1.0–1.5) for smokers, and 1.5 (1.2–1.9) for women who stopped smoking. Smoking intensity, measured as number of cigarettes smoked per day, was associated with pelvic pain in a dose–response pattern. Information about smoking was collected prospectively, which makes it unlikely that differential recall alone explains the results.
Conclusions Smoking was associated with pregnancy-related pelvic pain, with a dose–response pattern between reported smoking intensity and pelvic pain. These findings suggest a possible new risk factor for a common ailment during pregnancy.