Current debate on the use of antibiotic prophylaxis for caesarean section
Article first published online: 15 DEC 2010
© 2010 RCOG No claim to original US government works Journal compilation © RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology
BJOG: An International Journal of Obstetrics & Gynaecology
Special Issue: Infections in Pregnancy
Volume 118, Issue 2, pages 193–201, January 2011
How to Cite
Lamont, R., Sobel, J., Kusanovic, J., Vaisbuch, E., Mazaki-Tovi, S., Kim, S., Uldbjerg, N. and Romero, R. (2011), Current debate on the use of antibiotic prophylaxis for caesarean section. BJOG: An International Journal of Obstetrics & Gynaecology, 118: 193–201. doi: 10.1111/j.1471-0528.2010.02729.x
- Issue published online: 15 DEC 2010
- Article first published online: 15 DEC 2010
- Accepted 16 August 2010.
- caesarean section;
- surgical site infections
Please cite this paper as: Lamont R, Sobel J, Kusanovic J, Vaisbuch E, Mazaki-Tovi S, Kim S, Uldbjerg N, Romero R. Current debate on the use of antibiotic prophylaxis for caesarean section. BJOG 2011;118:193–201.
Caesarean delivery is frequently complicated by surgical site infections, endometritis and urinary tract infection. Most surgical site infections occur after discharge from the hospital, and are increasingly being used as performance indicators. Worldwide, the rate of caesarean delivery is increasing. Evidence-based guidelines recommended the use of prophylactic antibiotics before surgical incision. An exception is made for caesarean delivery, where narrow-range antibiotics are administered after umbilical cord clamping because of putative neonatal benefit. However, recent evidence supports the use of pre-incision, broad-spectrum antibiotics, which result in a lower rate of maternal morbidity with no disadvantage to the neonate.