Mycoplasmas in pregnancy
Article first published online: 23 NOV 2010
© 2010 The Authors Journal compilation © RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology
BJOG: An International Journal of Obstetrics & Gynaecology
Special Issue: Infections in Pregnancy
Volume 118, Issue 2, pages 164–174, January 2011
How to Cite
Taylor-Robinson, D. and Lamont, R. (2011), Mycoplasmas in pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 118: 164–174. doi: 10.1111/j.1471-0528.2010.02766.x
- Issue published online: 15 DEC 2010
- Article first published online: 23 NOV 2010
- Accepted 20 September 2010. Published Online 23 November 2010.
- Genital mycoplasmas;
- pregnancy outcome;
Please cite this paper as: Taylor-Robinson D, Lamont R. Mycoplasmas in pregnancy. BJOG 2011;118:164–174.
The genital mycoplasmas have been implicated in a number of adverse outcomes of pregnancy. Spontaneous preterm labour and preterm birth is an important contributor to perinatal mortality and morbidity. If Mycoplasma hominis plays an integral part in this problem, it is likely to contribute through its involvement with bacterial vaginosis. Ureaplasmas induce cytokines and inflammation, making a casual association compelling. The role of Mycoplasma genitalium and Mycoplasma fermentans is less clear, but M. genitalium is potentially pathogenic and should be treated if detected. There is considerable evidence for the role of M. hominis in post-partum and post-abortal sepsis, and for ureaplasmas causing chronic lung disease or death in very low birthweight infants. The role of the genital mycoplasmas in adverse outcomes of pregnancy is complicated by the presence or absence of bacterial vaginosis, and this association requires further research.