Short Communication

Placental site trophoblastic tumours and the concept of fertility preservation

  1. S Saso1,
  2. J Haddad1,
  3. P Ellis2,
  4. I Lindsay3,
  5. NJ Sebire3,
  6. A McIndoe4,
  7. MJ Seckl5,
  8. JR Smith4

Article first published online: 13 DEC 2011

DOI: 10.1111/j.1471-0528.2011.03230.x

Issue

BJOG: An International Journal of Obstetrics & Gynaecology

BJOG: An International Journal of Obstetrics & Gynaecology

Volume 119, Issue 3, pages 369–374, February 2012

Additional Information

How to Cite

Saso, S., Haddad, J., Ellis, P., Lindsay, I., Sebire, N., McIndoe, A., Seckl, M. and Smith, J. (2012), Placental site trophoblastic tumours and the concept of fertility preservation. BJOG: An International Journal of Obstetrics & Gynaecology, 119: 369–374. doi: 10.1111/j.1471-0528.2011.03230.x

Author Information

  1. 1

    Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Institute of Reproductive & Developmental Biology, Imperial College London

  2. 2

    Gynaecological Oncology, The Royal Surrey County Hospital NHS Foundation Trust, Guildford

  3. 3

    Department of Pathology, Imperial College Healthcare NHS Trust, London

  4. 4

    Consultant in Gynaecological Oncology, West London Gynaecological Cancer Centre, Queen Charlotte’s Hospital, Imperial College, London

  5. 5

    Department of Medical Oncology, Charing Cross Gestational Trophoblastic Disease Centre, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, UK

*Mr S Saso, Clinical Research Fellow, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Institute of Reproductive & Developmental Biology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. Email srdjan.saso@imperial.ac.uk

Publication History

  1. Issue published online: 12 JAN 2012
  2. Article first published online: 13 DEC 2011
  3. Accepted 22 September 2011. Published Online 13 December 2011.

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Keywords:

  • Fertility;
  • placental site trophoblastic tumour;
  • surgical technique

Please cite this paper as: Saso S, Haddad J, Ellis P, Lindsay I, Sebire N, McIndoe A, Seckl M, Smith J. Placental site trophoblastic tumours and the concept of fertility preservation. BJOG 2011; DOI: 10.1111/j.1471-0528.2011.03230.x.

The standard management of placental site trophoblastic tumours (PSTTs) is a radical hysterectomy with pelvic lymph node sampling. We present five cases to demonstrate a modified Strassman procedure (MSP), which is an alternative fertility-sparing technique. Each had a presumed solitary uterine PSTT. Following surgery, one patient remained in remission with her fertility intact. The other four underwent a completion hysterectomy because of incomplete excision of the disease. No residual disease was later found in two of these four uteri. This treatment should only be offered after extensive counselling. We intend to investigate the use of intraoperative frozen section analysis with cold-knife dissection in future.

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