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Abstract

—(1) Sciatic nerves of young rats have been shown to incorporate [14C]glycine in vitro into the protein fraction at a higher rate than nerves from adult rats under the same conditions.

(2) Whilst there is little change in the DNA content of the sciatic nerve of rats with age, there is a is noticeable decline in the RNA content with age.

(3) There a linear relationship between the specific activity of the protein fraction and the RNA content of the sciatic nerve under in vitro conditions.

(4) There is a decline in the specific activity of the protein fraction with age when expressed against DNA.

(5) A linear relationship exists between the logarithm of the specific activity and the length of the femur.