FROG SCIATIC NERVE MYELIN: A CHEMICAL CHARACTERIZATION

Authors

  • Marion Edmonds Smith,

    Corresponding author
    1. Department of Neurology, Veterans Administration Medical Center, Palo Alto, CA, U.S.A. and Stanford University School of Medicine, Stanford, CA 94305, U.S.A.
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  • Benson M. Curtis

    1. Department of Neurology, Veterans Administration Medical Center, Palo Alto, CA, U.S.A. and Stanford University School of Medicine, Stanford, CA 94305, U.S.A.
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    • 2

      Virginia Mason Research Center, Seattle, WA 98101, U.S.A.


To whom correspondence should be addressed.

Abstract

Abstract— The lipid and protein compositions of PNS myelin from two species of frogs, Xenopus laevis and Rana catesbiana, are compared with each other and with those of the rat. The relative proportions of PNS myelin lipids in the two frog species and rat are very similar except for a somewhat higher phosphatidyl choline content in frog myelin. The protein compositions of frog PNS myelin of the two species are also much alike, but a protein smaller than P2 is found in Xenopus, which is not seen in Rana. The results are discussed in terms of results found by others in other species and the compositions are compared with those of the corresponding CNS myelin.

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