G. P. Harper is a Research Fellow of the European Molecular Biology Organization.
Nerve Growth Factor: Biological Significance, Measurement and Distribution
Article first published online: 5 OCT 2006
Journal of Neurochemistry
Volume 34, Issue 1, pages 5–16, January 1980
How to Cite
Harper, G. P. and Thoenen, H. (1980), Nerve Growth Factor: Biological Significance, Measurement and Distribution. Journal of Neurochemistry, 34: 5–16. doi: 10.1111/j.1471-4159.1980.tb04615.x
- Issue published online: 5 OCT 2006
- Article first published online: 5 OCT 2006
- Nerve Growth Factor;
- Neuronal survival;
- Trophic messengers;
- Neuronal differentiation;
- Biological assay
NGF proteins probably act as informational molecules transferred from end organs to the neurons of the sympathetic nervous system. The direct demonstration of the NGF content of most end organs requires assays more sensitive than those currently available. The high levels of NGF produced by some organs are probably of some other physiological significance.