SEARCH

SEARCH BY CITATION

References

  • Alexianu M. E., Kozovska M. and Appel S. H. (2001) Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 57, 12821289.
  • Angelov D. N., Waibel S., Guntinas-Lichius O. et al. (2003) Therapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis. Proc. Natl Acad. Sci. U S A 100, 47904795.
  • Araujo D. M. and Cotman C. W. (1993) Trophic effects of interleukin-4-7 and -8 on hippocampal neuronal cultures: potential involvement of glia-derived factors. Brain Res. 600, 4955.
  • Bal-Price A. and Brown G. C. (2001) Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. J. Neurosci. 21, 64806491.
  • Barger S. W. and Basile A. S. (2001) Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. J. Neurochem. 76, 846854.
  • Benner E. J., Mosley R. L., Destache C. J. et al. (2004) Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease. Proc. Natl Acad. Sci. U S A 101, 94359440.
  • Block M. L. and Hong J. S. (2005) Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog. Neurobiol. 76, 7798.
  • Block M. L., Wu X., Pei Z., Li G., Wang T., Qin L., Wilson B., Yang J., Hong J. S. and Veronesi B. (2004) Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. FASEB J. 18, 16181620.
  • Brodie C., Goldreich N., Haiman T. and Kazimirsky G. (1998) Functional IL-4 receptors on mouse astrocytes: IL-4 inhibits astrocyte activation and induces NGF secretion. J. Neuroimmunol. 81, 2030.
  • Butovsky O., Talpalar A. E., Ben-Yaakov K. and Schwartz M. (2005) Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective. Mol. Cell Neurosci. 29, 381393.
  • Butovsky O., Landa G., Kunis G. et al. (2006) Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis. J. Clin. Invest. 116, 905915.
  • Byram S. C., Carson M. J., DeBoy C. A., Serpe C. J., Sanders V. M. and Jones K. J. (2004) CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation. J. Neurosci. 2004, 24 (18), 43334339.
  • Chao C. C., Molitor T. W. and Hu S. (1993) Neuroprotective role of IL-4 against activated microglia. J. Immunol. 151, 14731481.
  • Chao C. C., Hu S. and Peterson P. K. (1995) Modulation of human microglial cell superoxide production by cytokines. J. Leukoc. Biol. 58, 6570.
  • Clement A. M., Nguyen M. D., Roberts E. A. et al. (2003) Wild-type noneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science 302, 113117.
  • Denley A., Cosgrove L. J., Booker G. W., Wallace J. C. and Forbes B. E. (2005) Molecular interactions of the IGF system. Cytokine Growth. Factor Rev. 16, 421439.
  • Dore S., Bastianetto S., Kar S. and Quirion R. (1999) Protective and rescuing abilities of IGF-I and some putative free radical scavengers against beta-amyloid-inducing toxicity in neurons. Ann. N. Y. Acad. Sci. 890, 356364.
  • Ehrlich L. C., Hu S., Sheng W. S., Sutton R. L., Rockswold G. L., Peterson P. K. and Chao C. C. (1998) Cytokine regulation of human microglial cell IL-8 production. J. Immunol. 160, 19441948.
  • Floden A. M., Li S. and Combs C. K. (2005) Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors. J. Neurosci. 25, 25662575.
  • Furlan R., Poliani P. L., Marconi P. C., Bergami A., Ruffini F., Adorini L., Glorioso J. C., Comi G. and Martino G. (2001) Central nervous system gene therapy with interleukin-4 inhibits progression of ongoing relapsing-remitting autoimmune encephalomyelitis in Biozzi AB/H mice. Gene Ther. 8, 1319.
  • Gao H. M., Hong J. S., Zhang W. and Liu B. (2002) Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons. J. Neurosci. 22, 782790.
  • Gonzalez-Scarano F. and Baltuch G. (1999) Microglia as mediators of inflammatory and degenerative diseases. Annu. Rev. Neurosci. 22, 219240.
  • Henderson C. E., Bloch-Gallego E. and Camu W. (1995) Purification and culture of embryonic motor neurons, in Neural Cell Culture: a Practical Approach (Cohen, J., Wilkin, G., eds), pp. 6981. IRL Press, Oxford.
  • Henkel J. H., Beers D. R., Siklós L. and Appel S. H. (2006) The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Mol. Cell Neurosci. 31, 427437.
  • Jones K. J., Serpe C. J., Byram S. C., DeBoy C. A. and Sanders V. M. (2005) Role of the immune system in the maintenance of mouse facial motoneuron viability after nerve injury. Brain, Behavior, Immunity 19, 1219.
  • Kaspar B. K., Llado J., Sherkat N., Rothstein J. D. and Gage F. H. (2003) Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science 301, 839842.
  • Kitamura Y., Taniguchi T., Kimura H., Nomura Y. and Gebicke-Haerter P. J. (2000) Interleukin-4-inhibited mRNA expression in mixed rat glial and in isolated microglial cultures. J. Neuroimmunol. 106, 95104.
  • Koeberle P. D., Gauldie J. and Ball A. K. (2004) Effects of adenoviral-mediated gene transfer of interleukin-10, interleukin-4, and transforming growth factor-beta on the survival of axotomized retinal ganglion cells. Neuroscience 125, 903920.
  • Kuno R., Wang J., Kawanokuchi J., Takeuchi H., Mizuno T. and Suzumura A. (2005) Autocrine activation of microglia by tumor necrosis factor-alpha. J. Neuroimmunol. 162, 8996.
  • Le W. D., Rowe D., Xie W. J., Ortiz I., He Y. and Appel S. H. (2001) Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease. J. Neurosci. 21, 84478455.
  • Ledeboer A., Breve J. J., Poole S., Tilders F. J. and Van Dam A. M. (2000) Interleukin-10, interleukin-4, and transforming growth factor-beta differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells. Glia 30, 134142.
  • Lino M. M., Schneider C. and Caroni P. (2002) Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. J. Neurosci. 22, 48254832.
  • Mander P. K. and Brown G. C. (2005) Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration. J. Neuroinflammation 2, 2030.
  • Mayer A. M., Hall M. L., Lynch S. M., Gunasekera S. P., Sennett S. H. and Pomponi S. A. (2005) Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines. BMC Pharmacol. 5, 113.
  • Parvathenani L. K., Tertyshnikova S., Greco C. R., Roberts S. B., Robertson B. and Posmantur R. (2003) P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease. J. Biol. Chem. 278, 13 30913 317.
  • Pocock J. M. and Liddle A. C. (2001) Microglial signaling cascades in neurodegenerative disease, in Progress in Brain Research. Amsterdam (Castellano LopezB. and Nieto-SampedroM. eds.), Vol. 132, pp. 555565. Elsevier, New York.
  • Pramatarova A., Laganiere J., Roussel J., Brisebois K. and Rouleau G. A. (2001) Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J. Neurosci. 21, 33693374.
  • Sargsyan S. A., Monk P. N. and Shaw P. J. (2005) Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis. Glia 51, 241253.
  • Schwartz M., Shaked I., Fisher J., Mizrahi T., Schori H. (2003) Protective autoimmunity against the enemy within: fighting glutamate toxicity. Trends Neurosci. 26, 297302.
  • Shaw M. K., Lorens. J. B., Dhawan A. et al. (1997) Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis. J. Exp. Med. 185, 17111714.
  • Suzumura A., Sawada M., Itoh Y. and Marunouchi T. (1994) Interleukin-4 induces proliferation and activation of microglia but suppresses their induction of class II major histocompatibility complex antigen expression. J. Neuroimmunol. 53, 209218.
  • Town T., Vendrame M., Patel A. et al. (2002) Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid (1–42). J. Neuroimmunol. 132, 4959.
  • Wu X. F., Block M. L., Zhang W., Qin L., Wilson B., Zhang W. Q., Veronesi B. and Hong J. S. (2005) The role of microglia in paraquat-induced dopaminergic neurotoxicity. Antioxid. Redox Signal. 7, 654661.
  • Zhao W., Xie W., Le W. et al. (2004) Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. J. Neuropathol. Exp. Neurol. 63, 964977.
  • Zhou Y., Lin G. and Murtaugh M. P. (1995) Interleukin-4 suppresses the expression of macrophage NADPH oxidase heavy chain subunit (gp91-phox). Biochim. Biophys. Acta 1265, 4048.