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  • Adell A. and Artigas F. (1998) A microdialysis study of the in vivo release of 5-HT in the median raphe nucleus of the rat. Br. J. Pharmacol. 125, 13611367.
  • Aghajanian G. K. and Marek G. J. (1997) Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells. Neuropharmacology 36, 589599.
  • Aghajanian G. K. and Marek G. J. (1999) Serotonin-glutamate interactions: a new target for antipsychotic drugs. Neuropsychopharmacology 21, S122S133.
  • Aghajanian G. K. and Wang R. Y. (1977) Habenular and other midbrain raphe afferents demonstrated by a modified retrograde tracing technique. Brain Res. 122, 229242.
  • Amargós-Bosch M., Adell A., Bortolozzi A. and Artigas F. (2003) Stimulation of α1-adrenoceptors in the rat medial prefrontal cortex increases the local in vivo 5-hydroxytryptamine release: reversal by antipsychotic drugs. J. Neurochem. 87, 831842.
  • Amargós-Bosch M., Bortolozzi A., Puig M.V., Serrats J., Adell A., Celada P., Toth M., Mengod G. and Artigas F. (2004) Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex. Cereb. Cortex. 14, 281299.
  • Amargós-Bosch M., López-Gil X., Artigas F. and Adell A. (2007) Clozapine and olanzapine, but not haloperidol, suppress serotonin efflux in the medial prefrontal cortex elicited by phencyclidine and ketamine. Int. J. Neuropsychopharmacol. 9, 565573.
  • Andreasen N. C., O’Leary D. S., Flaum M., Nopoulos P., Watkins G. L., Boles Ponto LL. and Hichwa R. D. (1997) Hypofrontality in schizophrenia: distributed dysfunctional circuits in neuroleptic-naive patient. Lancet 349, 17301734.
  • Araneda R. and Andrade R. (1991) 5-Hydroxytryptamine2 and 5-hydroxytryptamine1A receptors mediate opposing responses on membrane excitability in rat association cortex. Neuroscience 40, 399.
  • Arnt J. and Skarsfeldt T. (1998) Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence. Neuropsychopharmacology 18, 63101.
  • Assié M. B., Dominguez H., Consul-Denjean N. and Newman-Tancredi A. (2006) In vivo occupancy of dopamine D2 receptors by antipsychotic drugs and novel compounds in the mouse striatum and olfactory tubercles. Naunyn-Schmiedberg’s Arch. Pharmacol. 373, 441450.
  • Bartha R., Williamson P. C., Drost D. J., Malla A., Carr T. J., Cortese L., Canaran G., Rylett R. J. and Neufeld R.W. (1997) Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy. Arch. Gen. Psychiatry 54, 959965.
  • Beique J. C., Campbell B., Perring P., Hamblin M. W., Walker P., Mladenovic L. and Andrade R. (2004) Serotonergic regulation of membrane potential in developing rat prefrontal cortex: coordinated expression of 5-hydroxytryptamine 5-HT1A, 5-HT2A, and 5-HT7 receptors. J. Neurosci. 24, 480717.
  • Bel N. and Artigas F. (1996) In vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. Microdialysis studies. J. Pharmacol. Exp. Ther. 278, 10641072.
  • Berendse H. W. and Groenewegen H. J. (1991) Restricted cortical termination fields of the midline and intralaminar thalamic nuclei in the rat. Neuroscience 42, 73102.
  • Bertolino A., Esposito G., Callicott J. H., Mattay V. S., Van Horn J. D., Frank J. A., Berman K. F. and Weinberger D.R. (2000) Specific relationship between prefrontal neuronal N-acetylaspartate and activation of the working memory cortical network in schizophrenia. Am. J. Psychiatry 157, 2633.
  • Bortolozzi A., Amargós-Bosch M., Adell A., Díaz-Mataix L., Serrats J., Pons S. and Artigas F. (2003) In vivo modulation of 5-hydroxytryptamine release in mouse prefrontal cortex by local 5-HT2A receptors. Effect of antipsychotic drugs. Eur. J. Neurosci. 18, 12351246.
  • Bubser M., de Brabander J. M., Timmerman W., Feenstra M. G., Erdtsieck-Ernste E. B., Rinkens A., van Uum J. F. and Westerink B. H. C. (1998) Disinhibition of the mediodorsal thalamus induces fos-like immunoreactivity in both pyramidal and GABA-containing neurons in the medial prefrontal cortex of rats, but does not affect prefrontal extracellular GABA levels. Synapse 30, 156165.
  • Bymaster F. P., Calligaro D. O., Falcone J. F., Marsh R. D., Moore N. A., Tye N. C., Seeman P. and Wong D. T. (1996) Radioreceptor binding profile of the atypical antipsychotic olanzapine. Neuropsychopharmacology 14, 8796.
  • Catafau A. M., Parellada E., Lomena F. J., Bernardo M., Pavia J., Ros D., Setoain J. and Gonzalez-Monclús E. (1994) Prefrontal and temporal blood flow in schizophrenia: resting and activation technetium-99 m-HMPAO SPECT patterns in young neuroleptic-naive patients with acute disease. J. Nucl. Med. 35, 935941.
  • Ceci A., Brambilla A., Duranti P., Grauert M., Grippa N. and Borsini F. (1999) Effect of antipsychotic drugs and selective dopaminergic antagonists on dopamine-induced facilitatory activity in prelimbic cortical pyramidal neurons. An in vitro study. Neuroscience 93, 107115.
  • Ceglia I., Carli M., Baviera M., Renoldi G., Calcagno E. and Invernizzi R. W. (2004) The 5-HT receptor antagonist M100,907 prevents extracellular glutamate rising in response to NMDA receptor blockade in the mPFC. J. Neurochem. 91, 189199.
  • Celada P., Puig M. V., Casanovas J. M., Guillazo G. and Artigas F. (2001) Control of dorsal raphe serotonergic neurons by the medial prefrontal cortex: Involvement of serotonin-1A, GABA(A: and glutamate receptors. J. Neurosci. 21, 99179929.
  • Chaki S., Funakoshi T., Yoshikawa R., Okuyama S., Kumagai T., Nakazato A., Nagamine M. and Tomisawa K. (1999) In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats. Neuropharmacology 38, 11851194.
  • Day H. E., Campeau S., Watson Jr S. J. and Akil H. (1997) Distribution of alpha-1A, alpha-1B and alpha-1D-adrenergic receptor mRNA in the rat brain and spinal cord. J. Chem. Neuroanat. 13, 115139.
  • Dierks T., Linden D.E., Jandl M., Formisano E., Goebel R., Lanfermann H. and Singer W. (1999) Activation of Heschl’s gyrus during auditory hallucinations. Neuron 22, 615621.
  • Domyancic A. V. and Morilak D. A. (1997) Distribution of alpha1A adrenergic receptor mRNA in the rat brain visualized by in situ hybridization. J. Comp. Neurol. 386, 358378.
  • Dursun S. M. and Handley S. L. (1996) Similarities in the pharmacology of spontaneous and DOI-induced head-shakes suggest 5HT2A receptors are active under physiological conditions. Psychopharmacology 128, 198205.
  • Erdtsieck-Ernste E. B., Feenstra M. G., Botterblom M. H., Van Uum H. F., Sluiter A. A. and Heinsbroek R. P. (1995) C-Fos expression in the rat brain after pharmacological stimulation of the rat “mediodorsal” thalamus by means of microdialysis. Neuroscience 66, 115131.
  • Farde L, Nordstrom A. L., Wiesel F. A., Pauli S, Halldin C and Sedvall G. (1992) Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. Arch. Gen. Psychiatry 49, 538544.
  • Fuster J. M. (2001) The prefrontal cortex-an update: time is of the essence. Neuron 30, 319333.
  • Gonzalez-Islas C. and Hablitz J. J. (2003) Dopamine enhances EPSCs in layer II-III pyramidal neurons in rat prefrontal cortex. J. Neurosci. 23, 867875.
  • Grace A. A. (2000) Gating of information flow within the limbic system and the pathophysiology of schizophrenia. Brain Res. Rev. 31, 330341.
  • Groenewegen H. J. and Uylings H. B. (2000) The prefrontal cortex and the integration of sensory limbic and autonomic information. Prog. Brain. Res. 126, 328.
  • Hajós M., Richards C. D., Szekely A. D. and Sharp T. (1998) An electrophysiological and neuroanatomical study of the medial prefrontal cortical projection to the midbrain raphe nuclei in the rat. Neuroscience 87, 95108.
  • Harrison P. J. and Lewis D. A. (2003) Neuropathology of schizophrenia, In Schizophrenia, 2nd edn (HirschS. J. and WeinbergerD. R., eds), pp. 310325 Blackwell Science, Oxford.
  • Hertel P., Nomikos G. G., Iurlo M. and Svensson T. H. (1996) Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain. Psychopharmacology 124, 7486.
  • Hervás I., Queiroz C. M., Adell A. and Artigas F. (2000) Role of uptake inhibition and autoreceptor activation in the control of 5-HT release in the frontal cortex and dorsal hippocampus of the rat. Br. J. Pharmacol. 130, 160166.
  • Jackson M. E., Homayoun H. and Moghaddam B. (2004) NMDA receptor hypofunction produces concomitant firing rate potentiation and burst activity reduction in the prefrontal cortex. P.N.A.S. 101, 84678472.
  • Jodo E., Chiang C. and Aston-Jones G. (1998) Potent excitatory influence of prefrontal cortex activity on noradrenergic locus coeruleus neurons. Neuroscience 83, 6379.
  • Jodo E., Suzuki Y., Katayama T., Hoshino K., Takeuchi S., Niwa S. and Kayama Y. (2005) Activation of medial prefrontal cortex by phencyclidine is mediated via a hippocampo-prefrontal pathway. Cereb. Cortex. 15, 663669.
  • Kapur S, Zipursky R. B, Remington G, Jones C., DaSilva J., Wilson A. A. and Houle S. (1998) 5-HT2 and D2 receptor occupancy of olanzapine in schizophrenia: a PET investigation. Am. J. Psychiatry 55, 921928.
  • Kargieman L., Celada P. and Artigas F. (2006) Increased activity of prefrontal pyramidal neurons after phencyclidine administration: reversal by clozapine. Eur. Neuropsychopharmacol. 16(Suppl. 1), S50S51.
  • Krystal J. H., D’Souza D. C., Mathalon D., Perry E., Belger A. and Hoffman R. (2003) NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development. Psychopharmacology 169, 215233.
  • Krystal J. H., Abi-Saab W., Perry E., D’Souza D. C., Liu N., Gueorguieva R., McDougall Hunsberger T., Belger A., Levine L. and Breier A. (2005) Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist LY354740, in healthy human subjects. Psychopharmacology 179, 303309.
  • Kuroda M., Yokofujita J. and Murakami K. (1998) An ultrastructural study of the neural circuit between the prefrontal cortex and the mediodorsal nucleus of the thalamus. Prog. Neurobiol. 54, 417458.
  • Lejeune F., Gobert A., Rivet J.M. and Millan M. J. (1994) Blockade of transmission at NMDA receptors facilitates the electrical and synthetic activity of ascending serotoninergic neurones. Brain. Res. 656, 427431.
  • Lewis D. A. and Lieberman J. A. (2000) Catching up on schizophrenia: natural history and neurobiology. Neuron 28, 325334.
  • Lewis D. A., Hashimoto T. and Volk D. W. (2005) Cortical inhibitory neurons and schizophrenia. Nat. Rev. Neurosci. 6, 312324.
  • Lópz-Gil J., Babot Z., Amargós-Bosch M., Suñol C., Artigas F. and Adell A. (2007) Clozapine and haloperidol differently suppress the MK-801-increased glutamatergic and serotonergic transmission in the medial prefrontal cortex of the rat. Neuropsychopharmacology Epub ahead of print – DOI:10.1038/sj.npp.1301356.
  • Maione S., Rossi F., Biggs C. S., Fowler L. J. and Whitton P. S. (1997) AMPA receptors modulate extracellular 5-hydroxytryptamine concentration and metabolism in rat striatum in vivo. Neurochem. Int. 30, 299304.
  • Marek G. J. and Aghajanian G. K. (1999) 5-HT2A receptor or alpha1-adrenoceptor activation induces excitatory postsynaptic currents in layer V pyramidal cells of the medial prefrontal cortex. Eur. J. Pharmacol. 367, 197206.
  • Martin P., Carlsson M. L. and Hjorth S. (1998) Systemic PCP treatment elevates brain extracellular 5-HT: a microdialysis study in awake rats. Neuroreport 9, 29852989.
  • Martín-Ruiz R., Puig M. V., Celada P., Shapiro D. A., Roth B. L., Mengod G. and Artigas F. (2001) Control of serotonergic function in medial prefrontal cortex by serotonin-2A receptors through a glutamate-dependent mechanism. J. Neurosci. 21, 98569866.
  • Meltzer H. Y. (1995) Role of serotonin in the action of atypical antipsychotic drugs. Clin. Neurosci. 3, 6475.
  • Meltzer H. Y. (1999) The role of serotonin in antipsychotic drug action. Neuropsychopharmacology 21, S106S115.
  • Millan M. J., Newman-Tancredi A., Brocco M. et al. (1998) S18126 ([2-[4-(2,3-dihydrobenzo[1,4]dioxin-6-yl)piperazin-1-ylmethyl]indan-2-yl]), a potent, selective and competitive antagonist at dopamine D4 receptors: an in vitro and in vivo comparison with L 745,870 (3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1H-pyrrolo[2, 3b]pyridine) and raclopride. J. Pharmacol.- Exp. Ther. 287, 167186.
  • Mirjana C., Baviera M., Invernizzi R.W. and Balducci C. (2004) The serotonin 5-HT2A receptor antagonist M100907 prevents impairment in attentional performance by NMDA receptor blockade in the rat prefrontal cortex. Neuropsychopharmacology 29, 16371647.
  • Moghaddam B. (2003) Bringing order to the glutamate chaos in schizophrenia. Neuron 40, 881884.
  • Moghaddam B. and Adams B.W. (1998) Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science 281, 13491352.
  • Moghaddam B. and Krystal J.H. (2003) The neurochemistry of schizophrenia, In Schizophrenia 2nd edn (HirschS. J. and WeinbergerD. R. eds), pp. 349364 Blackwell Science, Oxford.
  • Moghaddam B., Adams B. W., Verma A. and Daly D. (1997) Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with prefrontal cortex. J. Neurosci. 17, 29212927.
  • Moore H., West A. R. and Grace A. A. (1999) The regulation of forebrain dopamine transmission: relevance to the pathophysiology and psychopathology of schizophrenia. Biol. Psychiatry. 46, 4055.
  • O’Donnell P. (2003) Dopamine gating of forebrain neural ensembles. Eur. J. Neurosci. 17, 429435.
  • Patel D. R., Young A. M. and Croucher M. J. (2001) Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated stimulation of glutamate and GABA release in the rat striatum in vivo: a dual-label microdialysis study. Neuroscience 102, 11011111.
  • Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, Sidney.
  • Pieribone V. A., Nicholas A. P., Dagerlind A. and Hökfelt T. (1994) Distribution of alpha1 adrenoceptors in rat brain revealed by in situ hybridization experiments utilizing subtype-specific probes. J. Neurosci. 14, 42524268.
  • Pirot S., Jay T. M., Glowinski J. and Thierry A. M. (1994) Anatomical and electrophysiological evidence for an excitatory amino acid pathway from the thalamic mediodorsal nucleus to the prefrontal cortex in the rat. Eur. J. Neurosci. 6, 12251234.
  • Pompeiano M., Palacios J. M. and Mengod G. (1992) Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding. J. Neurosci. 12, 440453.
  • Pompeiano M., Palacios J. M. and Mengod G. (1994) Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors. Mol. Brain Res. 23, 163178.
  • Potkin S. G., Alva G., Fleming K., Anand R., Keator D., Carreon D., Doo M., Jin Y., Wu J. C. and Fallon J. H. (2002) A PET study of the pathophysiology of negative symptoms in schizophrenia. Positron emission tomography. Am. J. Psychiatry 159, 227237.
  • Puig M. V., Celada P., Díaz-Mataix L. and Artigas F. (2003) In vivo modulation of the activity of pyramidal neurons in the rat medial prefrontal cortex by 5-HT2A receptors. Relationship to thalamocortical afferents. Cereb. Cortex 13, 18701882.
  • Puig M. V., Artigas F. and Celada P. (2005) Modulation of the activity of pyramidal neurons in rat prefrontal cortex by raphe stimulation in vivo: involvement of serotonin and GABA. Cereb. Cortex 15, 114.
  • Ruat M., Traiffort E., Leurs R., Tardivel-Lacombe J., Diaz J., Arrang J. M., Schwartz and J. C. (1993) Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation. Proc. Natl Acad. Sci. U. S. A. 90, 854751.
  • Sakai K. and Crochet S. (2001) Differentiation of presumed serotonergic dorsal raphe neurons in relation to behavior and wake-sleep states. Neuroscience 104, 11411155.
  • Santana N., Bortolozzi A., Serrats J., Mengod G. and Artigas F. (2004) Expression of 5-HT1A and 5-HT2A receptors in pyramidal and GABAergic neurons of the rat prefrontal cortex. Cereb. Cortex 14, 11001109.
  • Satake S., Saitow F., Yamada J. and Konishi S. (2000) Synaptic activation of AMPA receptors inhibits GABA release from cerebellar interneurons. Nat. Neurosci. 3, 551558.
  • Schenk U., Verderio C., Benfenati F. and Matteoli M. (2003) Regulated delivery of AMPA receptor subunits to the presynaptic membrane. EMBO J. 22, 558568.
  • Schenk U., Menna E., Kim T., Passafaro M., Chang S., De Camilli P. and Matteoli M. (2005) A novel pathway for presynaptic mitogen-activated kinase activation via AMPA receptors. J. Neurosci. 25, 16541663.
  • Schotte A., Janssen P. F., Megens A. A. and Leysen J. E. (1993) Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography. Brain Res. 631, 191202.
  • Schreiber R., Brocco M., Audinot V., Gobert A., Veiga S. and Millan M.J. (1995) (1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists. J. Pharmaco. Exp. Ther. 273, 101112.
  • Shen Y., Monsma Jr F. J., Metcalf M. A., Jose P. A., Hamblin M. W. and Sibley DR. (1993) Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. J. Biol. Chem. 268, 82008204.
  • Shergill S. S., Brammer M. J., Williams S. C., Murray R. M. and McGuire P. K. (2000) Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging. Arch. Gen. Psychiatry 57, 10331038.
  • Suzuki Y., Jodo E., Takeuchi S., Niwa S. and Kayama Y. (2002) Acute administration of phencyclidine induces tonic activation of medial prefrontal cortex neurons in freely moving rats. Neuroscience 114, 769779.
  • Svensson T. H. (2003) Alpha-adrenoceptor modulation hypothesis of antipsychotic atypicality. Prog. Neuropsychopharmacol. Biol. Psychiatry. 27, 11451158.
  • Tao R., Ma Z. Y. and Auerbach S. B. (2000) Differential effect of local infusion of serotonin reuptake inhibitors in the raphe versus forebrain and the role of depolarization-induced release in increased extracellular serotonin. J. Pharmacol. Exp. Ther. 294, 571579.
  • Théberge J., Bartha R., Drost D. J. et al. (2002) Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers. Am. J. Psychiatry 59, 19441946.
  • Thierry A. M., Deniau J. M. and Feger J. (1979) Effects of stimulation of the frontal cortex on identified output VMT cells in the rat. Neurosci. Lett. 15, 103107.
  • Tsai G. and Coyle J. T. (2002) Glutamatergic mechanisms in schizophrenia. Annu. Rev. Pharmacol. Toxicol. 42, 165179.
  • Van der Werf Y. D., Witter M. P. and Groenewegen H. J. (2002) The intralaminar and midline nuclei of the thalamus. Anatomical and functional evidence for participation in processes of arousal and awareness. Brain Res. Rev. 39, 107140.
  • Varty G. B., Bakshi V. P. and Geyer M. A. (1999) M100907, a serotonin 5-HT2A receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and Wistar rats. Neuropsychopharmacology 20, 311321.
  • Wadenberg M. L., Hertel P., Fernhom R., Hygge Blakeman K., Ahlenius S. and Svensson T. H. (2000) Enhancement of antipsychotic-like effects by combined treatment with the α1-adrenoceptor antagonist prazosin and the dopamine D2 receptor antagonist raclopride in rats. J. Neural. Transm. 107, 12291238.
  • Weinberger D. R., Aloia M. S., Goldberg T. E. and Berman K. F. (1994) The frontal lobes and schizophrenia. J. Neuropsychiatry Clin. Neurosci. 6, 419427.
  • West A. R. and Grace A. A. (2002) Opposite influences of endogenous dopamine D1 and D2 receptor activation on activity states and electrophysiological properties of striatal neurons: studies combining in vivo intracellular recordings and reverse microdialysis. J. Neurosci. 22, 294304.