SEARCH

SEARCH BY CITATION

References

  • Amin J. and Weiss D. S. (1993) GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital. Nature 366, 565569.
  • Barnard E. A., Skolnick P., Olsen R. W., Mohler H., Sieghart W., Biggio G., Braestrup C., Bateson A. N. and Langer S. Z. (1998) International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function. Pharmacol. Rev. 50, 291313.
  • Barrera N. P., Herbert P., Henderson R. M., Martin I. L. and Edwardson J. M. (2005) Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT3 receptors. Proc. Natl Acad. Sci. USA 102, 1259512600.
  • Bencsits E., Ebert V., Tretter V. and Sieghart W. (1999) A significant part of native gamma-aminobutyric acidA receptors containing alpha4 subunits do not contain gamma or delta subunits. J. Biol. Chem. 274, 1961319616.
  • Bianchi M. T. and Macdonald R. L. (2002) Slow phases of GABA(A) receptor desensitisation: structural determinants and possible relevance for synaptic function. J. Physiol. 544, 318.
  • Bohme I., Rabe H. and Luddens H. (2004) Four amino acids in the alpha subunits determine the gamma-aminobutyric acid sensitivities of GABAA receptor subtypes. J. Biol. Chem. 279, 3519335200.
  • Boileau A. J, Kucken A. M., Evers A. R. and Czajkowski C. (1998) Molecular dissection of benzodiazepine binding and allosteric coupling using chimeric gamma-aminobutyric acidA receptor subunits. Mol. Pharmacol. 53, 295303.
  • Boileau A. J., Baur R., Sharkey L. M., Sigel E. and Czajkowski C. (2002) The relative amount of cRNA coding for gamma2 subunits affects stimulation by benzodiazepines in GABAA receptors expressed in Xenopus oocytes. Neuropharmacology 43, 695700.
  • Borghese C. M., Storustovu S., Ebert B., Herd M. B., Belelli D., Lambert J. J., Marshall G., Wafford K. A. and Harris R. A. (2006) The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. J. Pharmacol. Exp. Ther. 316, 13601368.
  • Brickley S. G., Revilla V, Cull-Candy S. G., Wisden W. and Farrant M. (2001) Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance. Nature 409, 8892.
  • Brown N., Kerby J., Bonnert T. P., Whiting P. J. and Wafford K. A. (2002) Pharmacological characterization of a novel cell line expressing human alpha4beta3delta GABAA receptors. Br. J. Pharmacol. 136, 965974.
  • Derry J. M., Dunn S. M. and Davies M. (2004) Identification of a residue in the gamma-aminobutyric acid type A receptor alpha subunit that differentially affects diazepam-sensitive and -insensitive benzodiazepine site binding. J. Neurochem. 88, 14311438.
  • Ernst M., Bruckner S., Boresch S. and Sieghart W. (2005) Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function. Mol. Pharmacol. 68, 12911300.
  • Essrich C., Lorez M., Benson J. A., Fritschy J. M. and Luscher B. (1998) Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin. Nat. Neurosci. 1, 563571.
  • Farrant M. and Nusser Z. (2005) Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors. Nat. Rev. Neurosci. 6, 215229.
  • Farrar S. J., Whiting P. J., Bonnert T. P. and McKernan R. M. (1999) Stoichiometry of a ligand-gated ion channel determined by fluorescence energy transfer. J. Biol. Chem. 274, 1010010104.
  • Feng H. J. and Macdonald R. L. (2004) Multiple actions of propofol on alphabetagamma and alphabetadelta GABAA receptors. Mol. Pharmacol. 66, 15171524.
  • Feng H. J., Bianchi M. T. and Macdonald R. L. (2004) Pentobarbital differentially modulates alpha1beta3delta and alpha1beta3gamma2 L GABAA receptor currents. Mol. Pharmacol. 66, 9881003.
  • Haas K. F. and Macdonald R. L. (1999) GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts. J. Physiol. 514, 2745.
  • Jones-Davis D. M., Song L., Gallagher M. J. and Macdonald R. L. (2005) Structural determinants of benzodiazepine allosteric regulation of GABA(A) receptor currents. J. Neurosci. 25, 80568065.
  • Korpi E. R. and Luddens H. (1993) Regional gamma-aminobutyric acid sensitivity of t-butylbicyclophosphoro[35S]thionate binding depends on γ-aminobutyric acidA receptor α subunit. Mol. Pharmacol. 44, 8792.
  • Lovick T. A., Griffiths J. L., Dunn S. M. and Martin I. L. (2005) Changes in GABA(A) receptor subunit expression in the midbrain during the oestrous cycle in Wistar rats. Neuroscience 131, 397405.
  • McKernan R. M. and Whiting P. J. (1996) Which GABAA-receptor subtypes really occur in the brain? Trends Neurosci. 19, 139143.
  • Mody I. (2001) Distinguishing between GABA(A) receptors responsible for tonic and phasic conductances. Neurochem. Res. 26, 907913.
  • Moore K. R. and Blakely R. D. (1994) Restriction site-independent formation of chimeras from homologous neurotransmitter-transporter cDNAs. Biotechniques 17, 130136.
  • Nayeem N., Green T. P., Martin I. L. and Barnard E. A. (1994) Quaternary structure of the native GABAA receptor determined by electron microscopic image analysis. J. Neurochem. 62, 815818.
  • Nusser Z., Sieghart W. and Somogyi P. (1998) Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells. J. Neurosci. 18, 16931703.
  • Saxena N. C. and Macdonald R. L. (1994) Assembly of GABAA receptor subunits: role of the delta subunit. J. Neurosci. 14, 70777086.
  • Sieghart W. (1995) Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes. Pharmacol. Rev. 47, 181234.
  • Sieghart W., Fuchs K., Tretter V., Ebert V., Jechlinger M., Hoger H. and Adamiker D. (1999) Structure and subunit composition of GABA(A) receptors. Neurochem. Int. 34, 379385.
  • Smith K. M., Ng A. M., Yao S. Y. et al. (2004) Electrophysiological characterization of a recombinant human Na+-coupled nucleoside transporter (hCNT1) produced in Xenopus oocytes. J. Physiol. 558, 807823.
  • Storustova S. I. and Ebert B. (2006) Pharmacological characterization of agonists at delta-containing GABAA receptors: functional selectivity for extrasynaptic receptors is dependent on the absence of gamma2. J. Pharmacol. Exp. Ther. 316, 13511359.
  • Sundstrom-Poromaa I., Smith D. H., Gong Q. H., Sabado T. N., Li X., Light A., Wiedmann M., Williams K. and Smith S. S. (2002) Hormonally regulated alpha4beta2delta GABAA receptors are a target for alcohol. Nat. Neurosci. 5, 721722.
  • Sur C., Farrar S. J., Kerby J., Whiting P. J., Atack J. R. and McKernan R. M. (1999) Preferential coassembly of alpha4 and delta subunits of the gamma-aminobutyric acid A receptor in rat thalamus. Mol. Pharmacol. 56, 110115.
  • Unwin N. (2005) Refined structure of the nicotinic acetylcholine receptor at 4A resolution. J. Mol. Biol. 346, 967989.
  • Wei W., Zhang N., Peng Z., Houser C. R. and Mody I. (2003) Perisynaptic localization of delta subunit-containing GABA(A) receptors and their activation by GABA spillover in the mouse dentate gyrus. J. Neurosci. 23, 1065010661.
  • Whiting P. J. (2003) GABA-A receptor subtypes in the brain: a paradigm for CNS drug discovery? Drug Discov. Today 8, 445450.