Transient adenosine efflux in the rat caudate–putamen
Article first published online: 10 JAN 2008
© 2008 The Authors. Journal Compilation © 2008 International Society for Neurochemistry
Journal of Neurochemistry
Volume 105, Issue 4, pages 1253–1263, May 2008
How to Cite
Cechova, S. and Venton, B. J. (2008), Transient adenosine efflux in the rat caudate–putamen. Journal of Neurochemistry, 105: 1253–1263. doi: 10.1111/j.1471-4159.2008.05223.x
- Issue published online: 10 JAN 2008
- Article first published online: 10 JAN 2008
- Received November 12, 2007; revised manuscript received January 3, 2008; accepted January 3, 2008.
Fig. S1 Cyclic voltammograms for A.) 1 μM Propentofylline, B.) 1 μM Histidine and C.) 1 μM ABT-702. Propentofylline and histidine were dissolved in Tris-buffer. ABT-702 was dissolved in 1% DMSO in Tris-buffer.
Fig. S2 Cyclic voltammograms for Adenosine (black), Adenosine and 0.1% DMSO (red) and Adenosine and 0.1% DMSO and 0.1 μM ABT-702 (blue). The DMSO slightly decreases electrode sensitivity to adenosine, but no further decreases were seen with addition of ABT-702.
Fig. S3 Calibration of oxygen saturated Tris-buffer in a flow injection analysis system. The oxygen saturated buffer contained 870 μM dissolved oxygen. The reduction peak for oxygen around -1.3 V is clearly visible in the CV.
Fig. S4 Color plots and cyclic voltammograms of adenosine and oxygen changes in vivo (A) before and (B) 30 min. after propentofylline (15 mg/kg). The potentials for oxygen and adenosine are labeled in the color plot of panel (A). The cyclic voltammograms were taken 3 seconds after the stimulus was administered and the adenosine and oxygen peaks are labeled in panel (A).
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