SEARCH

SEARCH BY CITATION

References

  • Adem A., Asblom A., Johansson G., Mbugua P. M. and Karlsson E. (1988) Toxins from the venom of the green mamba Dendroaspis angusticeps that inhibit the binding of quinuclidinyl benzilate to muscarinic acetylcholine receptors. Biochim. Biophys. Acta 968, 340345.
  • Adem A., Jolkkonen M., Bogdanovic N., Islam A. and Karlsson E. (1997) Localization of M1 muscarinic receptors in rat brain using selective muscarinic toxin-1. Brain Res. Bull. 44, 597601.
  • Birdsall N. J. and Lazareno S. (2005) Allosterism at muscarinic receptors: ligands and mechanisms. Mini Rev. Med. Chem. 5, 523543.
  • Bockaert J. and Pin J. P. (1999) Molecular tinkering of G protein-coupled receptors: an evolutionary success. EMBO J. 18, 17231729.
  • Bosmans F. and Tytgat J. (2007) Voltage-gated sodium channel modulation by scorpion alpha-toxins. Toxicon 49, 142158.
  • Bradley K. N. (2000) Muscarinic toxins from the green mamba. Pharmacol. Ther. 85, 87109.
  • Bradley K. N., Rowan E. G. and Harvey A. L. (2003) Effects of muscarinic toxins MT2 and MT7, from green mamba venom, on m1, m3 and m5 muscarinic receptors expressed in Chinese hamster ovary cells. Toxicon 41, 207215.
  • Carsi J. M., Valentine H. H. and Potter L. T. (1999) m2-Toxin: a selective ligand for M2 muscarinic receptors. Mol. Pharmacol. 56, 933937.
  • Catterall W. A., Cestele S., Yarov-Yarovoy V., Yu F. H., Konoki K. and Scheuer T. (2007) Voltage-gated ion channels and gating modifier toxins. Toxicon 49, 124141.
  • Caulfield M. P. and Birdsall N. J. (1998) International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol. Rev. 50, 279290.
  • Chan W. Y., McKinzie D. L., Bose S. et al. (2008) Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia. Proc. Natl Acad. Sci. USA 105, 1097810983.
  • Chen Z., Rogge G., Hague C., Alewood D., Colless B., Lewis R. J. and Minneman K. P. (2004) Subtype-selective noncompetitive or competitive inhibition of human alpha1-adrenergic receptors by rho-TIA. J. Biol. Chem. 279, 3532635333.
  • Christopoulos A. and Kenakin T. (2002) G protein-coupled receptor allosterism and complexing. Pharmacol. Rev. 54, 323374.
  • Christopoulos A., Lanzafame F. and Mitchelson F. (1998) Allosteric interactions at muscarinic cholinoceptors. Clin. Exp. Pharmacol. Physiol. 25, 185194.
  • Chung C., Wu B. N., Yang C. C. and Chang L. S. (2002) Muscarinic toxin-like proteins from Taiwan banded krait (Bungarus multicinctus) venom: purification, characterization and gene organization. Biol. Chem. 383, 13971406.
  • Craig A. G., Norberg T., Griffin D. et al. (1999) Contulakin-G, an O-glycosylated invertebrate neurotensin. J. Biol. Chem. 274, 1375213759.
  • Ducancel F. (2002) The sarafotoxins. Toxicon 40, 15411545.
  • Ducancel F. (2005) Endothelin-like peptides. Cell. Mol. Life Sci. 62, 28282839.
  • Fruchart-Gaillard C., Mourier G., Marquer C., Menez A. and Servent D. (2006) Identification of various allosteric interaction sites on M1 muscarinic receptor using 125I-Met35-oxidized muscarinic toxin 7. Mol. Pharmacol. 69, 16411651.
  • Fruchart-Gaillard C., Mourier G., Marquer C., Stura E., Birdsall N. J. and Servent D. (2008) Different interactions between MT7 toxin and the human muscarinic M1 receptor in its free and NMS-occupied states. Mol. Pharmacol. 74, 15541563.
  • Gilles N. and Ménez A. (2006) Peptides à propriétés d’antagoniste allostérique séléctif du récepteur adrénergique alpha1a et leurs applications (CEA, ed.), France. Patent application number FR20061584A.
  • Harvey A. L., Kornisiuk E., Bradley K. N., Cervenansky C., Duran R., Adrover M., Sanchez G. and Jerusalinsky D. (2002) Effects of muscarinic toxins MT1 and MT2 from green mamba on different muscarinic cholinoceptors. Neurochem. Res. 27, 15431554.
  • Heinrich J. N., Butera J. A., Carrick T. et al. (2009) Pharmacological comparison of muscarinic ligands: historical versus more recent muscarinic M(1)-preferring receptor agonists. Eur. J. Pharmacol. 605, 5356.
  • Huang L. F., Zheng J. B., Xu Y., Song H. T. and Yu C. X. (2008) A snake venom phospholipase A2 with high affinity for muscarinic acetylcholine receptors acts on guinea pig ileum. Toxicon 51, 10081016.
  • Jerusalinsky D. and Harvey A. L. (1994) Toxins from mamba venoms: small proteins with selectivities for different subtypes of muscarinic acetylcholine receptors. Trends Pharmacol. Sci. 15, 424430.
  • Jerusalinsky D., Cervenansky C., Walz R., Bianchin M. and Izquierdo I. (1993) A peptide muscarinic toxin from the green mamba venom shows agonist-like action in an inhibitory avoidance learning task. Eur. J. Pharmacol. 240, 103105.
  • Jerusalinsky D., Kornisiuk E., Alfaro P., Quillfeldt J., Alonso M., Verde E. R., Cervenansky C. and Harvey A. (1998) Muscarinic toxin selective for m4 receptors impairs memory in the rat. Neuroreport 9, 14071411.
  • Jerusalinsky D., Kornisiuk E., Alfaro P., Quillfeldt J., Ferreira A., Rial V. E., Duran R. and Cervenansky C. (2000) Muscarinic toxins: novel pharmacological tools for the muscarinic cholinergic system. Toxicon 38, 747761.
  • Jolkkonen M., Van Giersbergen P. L., Hellman U., Wernstedt C. and Karlsson E. (1994) A toxin from the green mamba Dendroaspis angusticeps: amino acid sequence and selectivity for muscarinic m4 receptors. FEBS Lett. 352, 9194.
  • Jolkkonen M., Adem A., Hellman U., Wernstedt C. and Karlsson E. (1995a) A snake toxin against muscarinic acetylcholine receptors: amino acid sequence, subtype specificity and effect on guinea-pig ileum. Toxicon 33, 399410.
  • Jolkkonen M., Van Giersbergen P. L., Hellman U., Wernstedt C., Oras A., Satyapan N., Adem A. and Karlsson E. (1995b) Muscarinic toxins from the black mamba Dendroaspis polylepis. Eur. J. Biochem. 234, 579585.
  • Jolkkonen M., Oras A., Toomela T., Karlsson E., Jarv J. and Akerman K. E. (2001) Kinetic evidence for different mechanisms of interaction of black mamba toxins MT alpha and MT beta with muscarinic receptors. Toxicon 39, 377382.
  • Joubert F. J. (1985) The amino acid sequence of protein CM-3 from Dendroaspis polylepis polylepis (black mamba) venom. Int. J. Biochem. 17, 695699.
  • Karlsson E., Jolkkonen M., Satyapan N., Adem A., Kumlin E., Hellman U. and Wernstedt C. (1994) Protein toxins that bind to muscarinic acetylcholine receptors. Ann. NY Acad. Sci. 710, 153161.
  • Karlsson E., Jolkonen M., Mulugeta E., Onali P. and Adem A. (2000) Snake toxins with high selectivity for subtypes of muscarinic acetylcholine receptors. Biochimie 82, 793806.
  • Kornisiuk E., Jerusalinsky D., Cervenansky C. and Harvey A. L. (1995) Binding of muscarinic toxins MTx1 and MTx2 from the venom of the green mamba Dendroaspis angusticeps to cloned human muscarinic cholinoceptors. Toxicon 33, 1118.
  • Krajewski J. L., Dickerson I. M. and Potter L. T. (2001) Site-directed mutagenesis of m1-toxin1: two amino acids responsible for stable toxin binding to M(1) muscarinic receptors. Mol. Pharmacol. 60, 725731.
  • Kukhtina V. V., Weise C., Muranova T. A., Starkov V. G., Franke P., Hucho F., Wnendt S., Gillen C., Tsetlin V. I. and Utkin Y. N. (2000) Muscarinic toxin-like proteins from cobra venom. Eur. J. Biochem. 267, 67846789.
  • Kukkonen A., Perakyla M., Akerman K. E. and Nasman J. (2004) Muscarinic toxin 7 selectivity is dictated by extracellular receptor loops. J. Biol. Chem. 279, 5092350929.
  • Langmead C. J., Fry V. A., Forbes I. T., Branch C. L., Christopoulos A., Wood M. D. and Herdon H. J. (2006) Probing the molecular mechanism of interaction between 4-n-butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the muscarinic M(1) receptor: direct pharmacological evidence that AC-42 is an allosteric agonist. Mol. Pharmacol. 69, 236246.
  • Langmead C. J., Watson J. and Reavill C. (2008) Muscarinic acetylcholine receptors as CNS drug targets. Pharmacol. Ther. 117, 232243.
  • Lee A. M., Jacoby D. B. and Fryer A. D. (2001) Selective muscarinic receptor antagonists for airway diseases. Curr. Opin. Pharmacol. 1, 223229.
  • Lewis R. J. and Garcia M. L. (2003) Therapeutic potential of venom peptides. Nat. Rev. Drug Discov. 2, 790802.
  • Liang J. S., Carsi-Gabrenas J., Krajewski J. L., McCafferty J. M., Purkerson S. L., Santiago M. P., Strauss W. L., Valentine H. H. and Potter L. T. (1996) Anti-muscarinic toxins from Dendroaspis angusticeps. Toxicon 34, 12571267.
  • Liang J., Gutierrez-Ford C. and Potter L. T. (2001) Sustained unilateral blockade of rat striatal M(1) muscarinic receptors with m1-toxin1 in vivo. Brain Res. 921, 211218.
  • Max S. I., Liang J. S. and Potter L. T. (1993a) Stable allosteric binding of m1-toxin to m1 muscarinic receptors. Mol. Pharmacol. 44, 11711175.
  • Max S. I., Liang J. S. and Potter L. T. (1993b) Purification and properties of m1-toxin, a specific antagonist of m1 muscarinic receptors. J. Neurosci. 13, 42934300.
  • Max S. I., Liang J. S., Valentine H. H. and Potter L. T. (1993c) Use of m1-toxin as a selective antagonist of m1 muscarinic receptors. J. Pharmacol. Exp. Ther. 267, 480485.
  • McDonough S. I. (2007) Gating modifier toxins of voltage-gated calcium channels. Toxicon 49, 202212.
  • Ménez R. and Ducruix A. (1993) A toxin that recognizes muscarinic acetylcholine receptors. Preparation and characterization of crystals suitable for structural analysis. J. Mol. Biol. 232, 997998.
  • Ménez A., Gillet D. and Grishin E. (2006) Toxins: Threats and Benefits. Research Signpost, Kerala, pp. 133.
  • Michel M. C., Oelke M. and Zinner N. (2005) Novel muscarinic antagonist to treat incontinence and/or overactive bladder. Drug Discov. Today Ther. Strateg. 2, 16.
  • Miyoshi S. and Tu A. T. (1996) Phospholipase A2 from Naja naja sputatrix venom is a muscarinic acetylcholine receptor inhibitor. Arch. Biochem. Biophys. 328, 1725.
  • Miyoshi S. and Tu A. T. (1999) Muscarinic acetylcholine receptor (mAChR) inhibitor from snake venom: interaction with subtypes of human mAChR. Arch. Biochem. Biophys. 369, 114118.
  • Miyoshi S. and Tu A. T. (2000) A snake venom inhibitor to muscarinic acetylcholine receptor (mAChR): isolation and interaction with cloned human mAChR. Arch. Biochem. Biophys. 377, 290295.
  • Mourier G., Dutertre S., Fruchart-Gaillard C., Ménez A. and Servent D. (2003) Chemical synthesis of MT1 and MT7 muscarinic toxins: critical role of Arg-34 in their interaction with M1 muscarinic receptor. Mol. Pharmacol. 63, 2635.
  • Nasman J., Jolkkonen M., Ammoun S., Karlsson E. and Akerman K. E. (2000) Recombinant expression of a selective blocker of M(1) muscarinic receptors. Biochem. Biophys. Res. Commun. 271, 435439.
  • Nielsen D. B., Dykert J., Rivier J. E. and McIntosh J. M. (1994) Isolation of Lys-conopressin-G from the venom of the worm-hunting snail, Conus imperialis. Toxicon 32, 845848.
  • Nirthanan S. and Gwee M. C. (2004) Three-finger alpha-neurotoxins and the nicotinic acetylcholine receptor, forty years on. J. Pharmacol. Sci. 94, 117.
  • Olianas M. C., Adem A., Karlsson E. and Onali P. (1996) Rat striatal muscarinic receptors coupled to the inhibition of adenylyl cyclase activity: potent block by the selective m4 ligand muscarinic toxin 3 (MT3). Br. J. Pharmacol. 118, 283288.
  • Olianas M. C., Maullu C., Adem A., Mulugeta E., Karlsson E. and Onali P. (2000) Inhibition of acetylcholine muscarinic M(1) receptor function by the M(1)-selective ligand muscarinic toxin 7 (MT-7). Br. J. Pharmacol. 131, 447452.
  • Olianas M. C., Adem A., Karlsson E. and Onali P. (2004) Action of the muscarinic toxin MT7 on agonist-bound muscarinic M1 receptors. Eur. J. Pharmacol. 487, 6572.
  • Rajagopalan N., Pung Y. F., Zhu Y. Z., Wong P. T., Kumar P. P. and Kini R. M. (2007) Beta-cardiotoxin: a new three-finger toxin from Ophiophagus hannah (king cobra) venom with beta-blocker activity. FASEB J. 21, 36853695.
  • Santiago M. P. and Potter L. T. (2001) Biotinylated m4-toxin demonstrates more M4 muscarinic receptor protein on direct than indirect striatal projection neurons. Brain Res. 894, 1220.
  • Scarr E. and Dean B. (2008) Muscarinic receptors: do they have a role in the pathology and treatment of schizophrenia? J. Neurochem. 107, 11881195.
  • Segalas I., Thai R., Menez R. and Vita C. (1995) A particularly labile Asp-Pro bond in the green mamba muscarinic toxin MTX2. Effect of protein conformation on the rate of cleavage. FEBS Lett. 371, 171175.
  • Ségalas I., Roumestand C., Zinn-Justin S., Gilquin B., Ménez R., Ménez A. and Toma F. (1995) Solution structure of a green mamba toxin that activates muscarinic acetylcholine receptors, as studied by nuclear magnetic resonance and molecular modeling. Biochemistry 34, 12481260.
  • Servent D. and Ménez A. (2001) Snake neurotoxins that interact with nicotinic acetylcholine receptors, in Handbook of Neurotoxicology, Vol. 1 (MassaroE. J. ed.), pp. 385425. Humana Press Inc., Totowa, NJ.
  • Sharpe I. A., Gehrmann J., Loughnan M. L. et al. (2001) Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nat. Neurosci. 4, 902907.
  • Shirey J. K., Xiang Z., Orton D. et al. (2008) An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission. Nat. Chem. Biol. 4, 4250.
  • Terlau H. and Olivera B. M. (2004) Conus venoms: a rich source of novel ion channel-targeted peptides. Physiol. Rev. 84, 4168.
  • Waelbroeck M., De Neef P., Domenach V., Vandermeers-Piret M. C. and Vandermeers A. (1996) Binding of the labelled muscarinic toxin 125I-MT1 to rat brain muscarinic M1 receptors. Eur. J. Pharmacol. 305, 187192.
  • Wang J. Q., Jolkkonen M. and McGinty J. F. (1997) The muscarinic toxin 3 augments neuropeptide mRNA in rat striatum in vivo. Eur. J. Pharmacol. 334, 4347.
  • Wirtshafter D. (2006) The selective m1 muscarinic antagonist MT-7 blocks pilocarpine-induced striatal Fos expression. Brain Res. 1085, 127131.