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α-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation

  1. Sebastian Jäger1,
  2. Stefanie Leuchtenberger2,
  3. Anne Martin1,
  4. Eva Czirr2,
  5. Johanna Wesselowski1,
  6. Marco Dieckmann2,
  7. Elaine Waldron1,
  8. Carsten Korth3,
  9. Edward H. Koo4,
  10. Michael Heneka5,
  11. Sascha Weggen2,
  12. Claus U. Pietrzik1

Article first published online: 5 OCT 2009

DOI: 10.1111/j.1471-4159.2009.06420.x

Issue

Journal of Neurochemistry

Journal of Neurochemistry

Volume 111, Issue 6, pages 1369–1382, December 2009

Additional Information

How to Cite

Jäger, S., Leuchtenberger, S., Martin, A., Czirr, E., Wesselowski, J., Dieckmann, M., Waldron, E., Korth, C., Koo, E. H., Heneka, M., Weggen, S. and Pietrzik, C. U. (2009), α-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Aβ generation. Journal of Neurochemistry, 111: 1369–1382. doi: 10.1111/j.1471-4159.2009.06420.x

Author Information

  1. 1

    Molecular Neurodegeneration Group, Institute of Physiological Chemistry and Pathobiochemistry, Johannes Gutenberg-University Mainz, Mainz, Germany

  2. 2

    Molecular Neuropathology Group, Department of Neuropathology, Heinrich Heine University, Düsseldorf, Germany

  3. 3

    Institute of Neuropathology, Heinrich Heine University, Düsseldorf, Germany

  4. 4

    Department of Neurosciences, University of California, San Diego, La Jolla, California, USA

  5. 5

    Department of Neurology, Clinical Neuroscience, University of Bonn, Bonn, Germany

*Address correspondence and reprint requests to: Claus U. Pietrzik, Institute of Physiological Chemistry and Pathobiochemistry, Molecular Neurodegeneration, Johannes-Gutenberg-University Mainz, Duesbergweg 6, D-55099 Mainz, Germany. E-mail: pietrzik@uni-mainz.de

Publication History

  1. Issue published online: 20 NOV 2009
  2. Article first published online: 5 OCT 2009
  3. Received June 26, 2009, revised manuscript received September 10, 2009, accepted September 11, 2009.

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