Functional magnetic resonance imaging and c-Fos mapping in rats following a glucoprivic dose of 2-deoxy-d-glucose
Version of Record online: 17 MAR 2010
© 2010 The Authors. Journal Compilation © 2010 International Society for Neurochemistry
Journal of Neurochemistry
Volume 113, Issue 5, pages 1123–1132, June 2010
How to Cite
Dodd, G. T., Williams, S. R. and Luckman, S. M. (2010), Functional magnetic resonance imaging and c-Fos mapping in rats following a glucoprivic dose of 2-deoxy-d-glucose. Journal of Neurochemistry, 113: 1123–1132. doi: 10.1111/j.1471-4159.2010.06671.x
- Issue online: 4 MAY 2010
- Version of Record online: 17 MAR 2010
- Received December 23, 2009; revised manuscript received February 25, 2010; accepted February 25, 2010.
Appendix S1. Supplementary Materials and Methods.
Figure S1. Line graph illustrating time course changes of (a) tcpCO2 and (b) tcpO2 following subcutaneous administration of vehicle, or 2-DG (200 mg/kg) in α-chloralose anaesthetized rats (n = 7). An initial 15-min baseline period was acquired before drugs were injected (vertical dotted line). Results are presented as percentage change relative to baseline values (100%). Horizontal dotted line represents threshold level as described by Cabrer et al. (2005) by which BOLD signal is lost if tcpCO2 levels exceed 20% above baseline (Ramos-Cabrer et al. 2005). Error bars show SEM.
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