SEARCH

SEARCH BY CITATION

References

  • Barger S. W. and Harmon A. D. (1997) Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 388, 878881.
  • Barger S. W. and Mattson M. P. (1995) The secreted form of the Alzheimer’s beta-amyloid precursor protein stimulates a membrane-associated guanylate cyclase. Biochem. J. 311(Pt 1), 4547.
  • Barger S. W., Fiscus R. R., Ruth P., Hofmann F. and Mattson M. P. (1995) Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor. J. Neurochem. 64, 20872096.
  • Bayer T. A., Schafer S., Simons A. et al. (2003) Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice. Proc. Natl. Acad. Sci. U S A 100, 1418714192.
  • Bernier P. J., Bedard A., Vinet J., Levesque M. and Parent A. (2002) Newly generated neurons in the amygdala and adjoining cortex of adult primates. Proc. Natl. Acad. Sci. USA 99, 1146411469.
  • Bi X., Gall C. M., Zhou J. and Lynch G. (2002) Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists. Neuroscience 112, 827840.
  • Bu G., Cam J. and Zerbinatti C. (2006) LRP in amyloid-beta production and metabolism. Ann. N Y Acad. Sci. 1086, 3553.
  • Bush A. I., Multhaup G., Moir R. D., Williamson T. G., Small D. H., Rumble B., Pollwein P., Beyreuther K. and Masters C. L. (1993) A novel zinc(II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer’s disease. J. Biol. Chem. 268, 1610916112.
  • Buxbaum J. N., Ye Z., Reixach N., Friske L., Levy C., Das P., Golde T., Masliah E., Roberts A. R. and Bartfai T. (2008) Transthyretin protects Alzheimer’s mice from the behavioral and biochemical effects of Abeta toxicity. Proc. Natl. Acad. Sci. USA 105, 26812686.
  • Caillé I., Allinquant B., Dupont E., Bouillot C., Langer A., Muller U. and Prochiantz A. (2004) Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone. Development 131, 21732181.
  • Cappai R., Cheng F., Ciccotosto G. D., Needham B. E., Masters C. L., Multhaup G., Fransson L. A. and Mani K. (2005) The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo. J. Biol. Chem. 280, 1391313920.
  • Chasseigneaux S., Dinc L., Rose C., Chabret C., Coulpier F., Topilko P., Mauger G. and Allinquant B. (2011) Secreted amyloid precursor protein beta and secreted amyloid precursor protein alpha induce axon outgrowth in vitro through Egr1 signaling pathway. PLoS ONE 6, e16301.
  • Chen Y. and Dong C. (2009) Abeta40 promotes neuronal cell fate in neural progenitor cells. Cell Death Differ. 16, 386394.
  • Cheng G., Yu Z., Zhou D. and Mattson M. P. (2002) Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein. Exp. Neurol. 175, 407414.
  • Clarris H. J., Nurcombe V., Small D. H., Beyreuther K. and Masters C. L. (1994) Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer’s disease from hippocampal explants. J. Neurosci. Res. 38, 248258.
  • Clarris H. J., Cappai R., Heffernan D., Beyreuther K., Masters C. L. and Small D. H. (1997) Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer’s disease by deletion mutagenesis and peptide mapping. J. Neurochem. 68, 11641172.
  • Cole G. M., Galasko D., Shapiro I. P. and Saitoh T. (1990) Stimulated platelets release amyloid beta-protein precursor. Biochem. Biophys. Res. Commun. 170, 288295.
  • Copanaki E., Chang S., Vlachos A., Tschape J. A., Muller U. C., Kogel D. and Deller T. (2010) sAPPalpha antagonizes dendritic degeneration and neuron death triggered by proteasomal stress. Mol. Cell. Neurosci. 44, 386393.
  • Corrigan F., Pham C. L., Vink R., Blumbergs P. C., Masters C. L., van den Heuvel C. and Cappai R. (2011) The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains. Brain Res. 1378, 137143.
  • Culicchia F., Cui J. G., Li Y. Y. and Lukiw W. J. (2008) Upregulation of beta-amyloid precursor protein expression in glioblastoma multiforme. Neuroreport 19, 981985.
  • Freude K. K., Penjwini M., Davis J. L., LaFerla F. M. and Blurton-Jones M. (2011) Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells. J. Biol. Chem. 286, 2426424274.
  • Furukawa K., Sopher B. L., Rydel R. E., Begley J. G., Pham D. G., Martin G. M., Fox M. and Mattson M. P. (1996a) Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain. J. Neurochem. 67, 18821896.
  • Furukawa K., Barger S. W., Blalock E. M. and Mattson M. P. (1996b) Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein. Nature 379, 7478.
  • Gakhar-Koppole N., Hundeshagen P., Mandl C., Weyer S. W., Allinquant B., Muller U. and Ciccolini F. (2008) Activity requires soluble amyloid precursor protein alpha to promote neurite outgrowth in neural stem cell-derived neurons via activation of the MAPK pathway. Eur. J. Neurosci. 28, 871882.
  • Giri R., Shen Y., Stins M., Du Yan S., Schmidt A. M., Stern D., Kim K. S., Zlokovic B. and Kalra V. K. (2000) beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1. Am. J. Physiol. Cell Physiol. 279, C1772C1781.
  • Giuffrida M. L., Caraci F., Pignataro B. et al. (2009) Beta-amyloid monomers are neuroprotective. J. Neurosci. 29, 1058210587.
  • Goodman Y. and Mattson M. P. (1994) Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury. Exp. Neurol. 128, 112.
  • Gralle M., Oliveira C. L., Guerreiro L. H. et al. (2006) Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein. J. Mol. Biol. 357, 493508.
  • Greenberg S. M. and Kosik K. S. (1995) Secreted beta-APP stimulates MAP kinase and phosphorylation of tau in neurons. Neurobiol. Aging 16, 403407; discussion 407–408.
  • Guenette S., Chang Y., Hiesberger T., Richardson J. A., Eckman C. B., Eckman E. A., Hammer R. E. and Herz J. (2006) Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J. 25, 420431.
  • Hansel D. E., Rahman A., Wehner S., Herzog V., Yeo C. J. and Maitra A. (2003) Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence cellular proliferation. Cancer Res. 63, 70327037.
  • Hartmann D., De Strooper B. and Saftig P. (1999) Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly. Curr. Biol. 9, 719727.
  • Hayashi Y., Kashiwagi K., Ohta J., Nakajima M., Kawashima T. and Yoshikawa K. (1994) Alzheimer amyloid protein precursor enhances proliferation of neural stem cells from fetal rat brain. Biochem. Biophys. Res. Commun. 205, 936943.
  • Heber S., Herms J., Gajic V. et al. (2000) Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. J. Neurosci. 20, 79517963.
  • Hebert S. S., Horre K., Nicolai L., Papadopoulou A. S., Mandemakers W., Silahtaroglu A. N., Kauppinen S., Delacourte A. and De Strooper B. (2008) Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer’s disease correlates with increased BACE1/beta-secretase expression. Proc. Natl. Acad. Sci. USA 105, 64156420.
  • Herms J., Anliker B., Heber S., Ring S., Fuhrmann M., Kretzschmar H., Sisodia S. and Muller U. (2004) Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members. EMBO J. 23, 41064115.
  • Hesse L., Beher D., Masters C. L. and Multhaup G. (1994) The beta A4 amyloid precursor protein binding to copper. FEBS Lett. 349, 109116.
  • Hoffmann J., Pietrzik C. U., Kummer M. P., Twiesselmann C., Bauer C. and Herzog V. (1999) Binding and selective detection of the secretory N-terminal domain of the alzheimer amyloid precursor protein on cell surfaces. J. Histochem. Cytochem. 47, 373382.
  • Hornsten A., Lieberthal J., Fadia S. et al. (2007) APL-1, a Caenorhabditis elegans protein related to the human beta-amyloid precursor protein, is essential for viability. Proc. Natl. Acad. Sci. USA 104, 19711976.
  • Ishida A., Furukawa K., Keller J. N. and Mattson M. P. (1997) Secreted form of beta-amyloid precursor protein shifts the frequency dependency for induction of LTD, and enhances LTP in hippocampal slices. Neuroreport 8, 21332137.
  • Jin L. W., Ninomiya H., Roch J. M., Schubert D., Masliah E., Otero D. A. and Saitoh T. (1994) Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension. J. Neurosci. 14, 54615470.
  • Jones M. W., Errington M. L., French P. J., Fine A., Bliss T. V., Garel S., Charnay P., Bozon B., Laroche S. and Davis S. (2001) A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories. Nat. Neurosci. 4, 289296.
  • Kaden D., Munter L. M., Joshi M. et al. (2008) Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP. J. Biol. Chem. 283, 72717279.
  • Kamenetz F., Tomita T., Hsieh H., Seabrook G., Borchelt D., Iwatsubo T., Sisodia S. and Malinow R. (2003) APP processing and synaptic function. Neuron 37, 925937.
  • Kienlen-Campard P., Tasiaux B., Van Hees J. et al. (2008) Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs. J. Biol. Chem. 283, 77337744.
  • Klier F. G., Cole G., Stallcup W. and Schubert D. (1990) Amyloid beta-protein precursor is associated with extracellular matrix. Brain Res. 515, 336342.
  • von Koch C. S., Zheng H., Chen H., Trumbauer M., Thinakaran G., van der Ploeg L. H., Price D. L. and Sisodia S. S. (1997) Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol. Aging 18, 661669.
  • Lafont F., Rouget M., Triller A., Prochiantz A. and Rousselet A. (1992) In vitro control of neuronal polarity by glycosaminoglycans. Development 114, 1729.
  • Lafont F., Rouget M., Rousselet A., Valenza C. and Prochiantz A. (1993) Specific responses of axons and dendrites to cytoskeleton perturbations: an in vitro study. J. Cell Sci. 104(Pt 2), 433443.
  • Lauren J., Gimbel D. A., Nygaard H. B., Gilbert J. W. and Strittmatter S. M. (2009) Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature 457, 11281132.
  • Lee S., Xue Y., Hu J., Wang Y., Liu X., Demeler B. and Ha Y. (2011) The E2 domains of APP and APLP1 share a conserved mode of dimerization. Biochemistry 50, 54535464.
  • Li Z. W., Stark G., Götz J., Rülicke T., Gschwind M., Huber G., Müller U. and Weissmann C. (1996) Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells. Proc. Natl. Acad. Sci. USA 93, 61586162.
  • Li H., Wang B., Wang Z., Guo Q., Tabuchi K., Hammer R. E., Sudhof T. C. and Zheng H. (2010) Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP. Proc. Natl. Acad. Sci. U S A 107, 1736217367.
  • Löffler J. and Huber G. (1992) Beta-amyloid precursor protein isoforms in various rat brain regions and during brain development. J. Neurochem. 59, 13161324.
  • Mattson M. P., Cheng B., Culwell A. R., Esch F. S., Lieberburg I. and Rydel R. E. (1993) Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein. Neuron 10, 243254.
  • Meng J. Y., Kataoka H., Itoh H. and Koono M. (2001) Amyloid beta protein precursor is involved in the growth of human colon carcinoma cell in vitro and in vivo. Int. J. Cancer 92, 3139.
  • Meziane H., Dodart J. C., Mathis C., Little S., Clemens J., Paul S. M. and Ungerer A. (1998) Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice. Proc. Natl. Acad. Sci. USA 95, 1268312688.
  • Mills J. and Reiner P. B. (1999) Regulation of amyloid precursor protein cleavage. J. Neurochem. 72, 443460.
  • Miners J. S., Baig S., Palmer J., Palmer L. E., Kehoe P. G. and Love S. (2008) Abeta-degrading enzymes in Alzheimer’s disease. Brain Pathol. 18, 240252.
  • Moechars D., Lorent K., De Strooper B., Dewachter I. and Van Leuven F. (1996) Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice. EMBO J. 15, 12651274.
  • Moechars D., Lorent K., Dewachter I., Baekelandt V., De Strooper B. and Van Leuven F. (1998) Transgenic mice expressing an alpha-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder. Behav. Brain Res. 95, 5564.
  • Monning U., Konig G., Prior R., Mechler H., Schreiter-Gasser U., Masters C. L. and Beyreuther K. (1990) Synthesis and secretion of Alzheimer amyloid beta A4 precursor protein by stimulated human peripheral blood leucocytes. FEBS Lett. 277, 261266.
  • Monning U., Konig G., Banati R. B., Mechler H., Czech C., Gehrmann J., Schreiter-Gasser U., Masters C. L. and Beyreuther K. (1992) Alzheimer beta A4-amyloid protein precursor in immunocompetent cells. J. Biol. Chem. 267, 2395023956.
  • Müller Z. W., Cristina N., Li Z. W., Wolfer D. P., Lipp H. P., Rülicke T., Brandner S., Aguzzi A. and Weissmann C. (1994) Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene. Cell 79, 755765.
  • Multhaup G., Bush A. I., Pollwein P. and Masters C. L. (1994) Interaction between the zinc (II) and the heparin binding site of the Alzheimer’s disease beta A4 amyloid precursor protein (APP). FEBS Lett. 355, 151154.
  • Multhaup G., Schlicksupp A., Hesse L., Beher D., Ruppert T., Masters C. L. and Beyreuther K. (1996) The amyloid precursor protein of Alzheimer’s disease in the reduction of copper(II) to copper(I). Science 271, 14061409.
  • Munter L. M., Voigt P., Harmeier A., Kaden D., Gottschalk K. E., Weise C., Pipkorn R., Schaefer M., Langosch D. and Multhaup G. (2007) GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42. EMBO J. 26, 17021712.
  • Narindrasorasak S., Lowery D., Gonzalez-DeWhitt P., Poorman R. A., Greenberg B. and Kisilevsky R. (1991) High affinity interactions between the Alzheimer’s beta-amyloid precursor proteins and the basement membrane form of heparan sulfate proteoglycan. J. Biol. Chem. 266, 1287812883.
  • Nikolaev A., McLaughlin T., O’Leary D. D. and Tessier-Lavigne M. (2009) APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature 457, 981989.
  • Ninomiya H., Roch J. M., Jin L. W. and Saitoh T. (1994) Secreted form of amyloid beta/A4 protein precursor (APP) binds to two distinct APP binding sites on rat B103 neuron-like cells through two different domains, but only one site is involved in neuritotropic activity. J. Neurochem. 63, 495500.
  • Ohsawa I., Takamura C., Morimoto T., Ishiguro M. and Kohsaka S. (1999) Amino-terminal region of secreted form of amyloid precursor protein stimulates proliferation of neural stem cells. Eur. J. Neurosci. 11, 19071913.
  • Pietrzik C. U., Hoffmann J., Stober K., Chen C. Y., Bauer C., Otero D. A., Roch J. M. and Herzog V. (1998) From differentiation to proliferation: the secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells. Proc. Natl. Acad. Sci. USA 95, 17701775.
  • Portelius E., Mattsson N., Andreasson U., Blennow K. and Zetterberg H. (2011) Novel Abeta Isoforms in Alzheimer s Disease -Their Role in Diagnosis and Treatment. Curr. Pharm. Des. 17, 25942602.
  • Ring S., Weyer S. W., Kilian S. B. et al. (2007) The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. J. Neurosci. 27, 78177826.
  • Roch J. M., Masliah E., Roch-Levecq A. C., Sundsmo M. P., Otero D. A., Veinbergs I. and Saitoh T. (1994) Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor. Proc. Natl. Acad. Sci. USA 91, 74507454.
  • Rohe M., Carlo A. S., Breyhan H. et al. (2008) Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis. J. Biol. Chem. 283, 1482614834.
  • Rossjohn J., Cappai R., Feil S. C. et al. (1999) Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat. Struct. Biol. 6, 327331.
  • Saitoh T., Sundsmo M., Roch J. M., Kimura N., Cole G., Schubert D., Oltersdorf T. and Schenk D. B. (1989) Secreted form of amyloid beta protein precursor is involved in the growth regulation of fibroblasts. Cell 58, 615622.
  • Schubert D., LaCorbiere M., Saitoh T. and Cole G. (1989) Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate. Proc. Natl. Acad. Sci. USA 86, 20662069.
  • Small D. H., Nurcombe V., Moir R., Michaelson S., Monard D., Beyreuther K. and Masters C. L. (1992) Association and release of the amyloid protein precursor of Alzheimer’s disease from chick brain extracellular matrix. J. Neurosci. 12, 41434150.
  • Small D. H., Nurcombe V., Reed G., Clarris H., Moir R., Beyreuther K. and Masters C. L. (1994) A heparin-binding domain in the amyloid protein precursor of Alzheimer’s disease is involved in the regulation of neurite outgrowth. J. Neurosci. 14, 21172127.
  • Smith-Swintosky V. L., Pettigrew L. C., Craddock S. D., Culwell A. R., Rydel R. E. and Mattson M. P. (1994) Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury. J. Neurochem. 63, 781784.
  • Soba P., Eggert S., Wagner K. et al. (2005) Homo- and heterodimerization of APP family members promotes intercellular adhesion. EMBO J. 24, 36243634.
  • Sotthibundhu A., Li Q. X., Thangnipon W. and Coulson E. J. (2009) Abeta(1-42) stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor. Neurobiol. Aging 30, 19751985.
  • Sprecher C. A., Grant F. J., Grimm G., O’Hara P. J., Norris F., Norris K. and Foster D. C. (1993) Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family. Biochemistry 32, 44814486.
  • Takayama K., Tsutsumi S., Suzuki T. et al. (2009) Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth. Cancer Res. 69, 137142.
  • Taylor C. J., Ireland D. R., Ballagh I., Bourne K., Marechal N. M., Turner P. R., Bilkey D. K., Tate W. P. and Abraham W. C. (2008) Endogenous secreted amyloid precursor protein-alpha regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory. Neurobiol. Dis. 31, 250260.
  • Treiber C., Simons A., Strauss M., Hafner M., Cappai R., Bayer T. A. and Multhaup G. (2004) Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer’s disease. J. Biol. Chem. 279, 5195851964.
  • Van Nostrand W. E. (1995) Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid beta-protein precursor. Thromb. Res. 78, 4353.
  • Van Nostrand W. E., Schmaier A. H., Farrow J. S., Cines D. B. and Cunningham D. D. (1991) Protease nexin-2/amyloid beta-protein precursor in blood is a platelet-specific protein. Biochem. Biophys. Res. Commun. 175, 1521.
  • Vincent B. and Govitrapong P. (2011) Activation of the alpha-secretase processing of AbetaPP as a therapeutic approach in Alzheimer’s disease. J. Alzheimers Dis. 24(Suppl. 2), 7594.
  • Wang H. Y., Lee D. H., Davis C. B. and Shank R. P. (2000) Amyloid peptide Abeta (1-42) binds selectively and with picomolar affinity to alpha7 nicotinic acetylcholine receptors. J. Neurochem. 75, 11551161.
  • Wasco W., Gurubhagavatula S., Paradis M. D., Romano D. M., Sisodia S. S., Hyman B. T., Neve R. L. and Tanzi R. E. (1993) Isolation and characterization of APLP2 encoding a homologue of the Alzheimer’s associated amyloid beta protein precursor. Nat. Genet. 5, 95100.
  • Weyer S. W., Klevanski M., Delekate A. et al. (2011) APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP. EMBO J. 30, 22662280.
  • White A. R., Reyes R., Mercer J. F., Camakaris J., Zheng H., Bush A. I., Multhaup G., Beyreuther K., Masters C. L. and Cappai R. (1999) Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice. Brain Res. 842, 439444.
  • Whitson J. S., Selkoe D. J. and Cotman C. W. (1989) Amyloid beta protein enhances the survival of hippocampal neurons in vitro. Science 243, 14881490.
  • Williamson T. G., Nurcombe V., Beyreuther K., Masters C. L. and Small D. H. (1995) Affinity purification of proteoglycans that bind to the amyloid protein precursor of Alzheimer’s disease. J. Neurochem. 65, 22012208.
  • Williamson T. G., Mok S. S., Henry A., Cappai R., Lander A. D., Nurcombe V., Beyreuther K., Masters C. L. and Small D. H. (1996) Secreted glypican binds to the amyloid precursor protein of Alzheimer’s disease (APP) and inhibits APP-induced neurite outgrowth. J. Biol. Chem. 271, 3121531221.
  • Yankner B. A., Duffy L. K. and Kirschner D. A. (1990) Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science 250, 279282.
  • Young-Pearse T. L., Bai J., Chang R., Zheng J. B., LoTurco J. J. and Selkoe D. J. (2007) A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. J. Neurosci. 27, 1445914469.
  • Young-Pearse T. L., Chen A. C., Chang R., Marquez C. and Selkoe D. J. (2008) Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1. Neural Dev. 3, 15.
  • Zhao W. Q., Santini F., Breese R. et al. (2010) Inhibition of calcineurin-mediated endocytosis and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors prevents amyloid beta oligomer-induced synaptic disruption. J. Biol. Chem. 285, 76197632.