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Figure S1. Representative electrophoretogram of total RNA extracted from cerebral cortex or peri-infarct region of mice. Two bands of 28S and 18S ribosomal RNA could be found in normoxic control, hypoxic preconditioning (HPC), MCAO-induced focal ischemia (I) and HPC+I groups (n = 12 per group).

Figure S2. OGD induced cell injury and modulated miR-615-3p expression in cultured N2A cells. N2A cells were exposed to OGD for 2 or 4 h and reoxygenation for 24 h. N2A cell injuries were detected by MTT (A) and LDH (B) assays (*p < 0.05 vs normoxic control, n = 6 per group). (C) miR-615-3p levels were determined by qRT-PCR after transfection of vehicle control, pre-miR control, pre-miR-615-3p, anti-miR control, or anti-miR-615-3p at a final concentration of 30 nM for 48 h (*p < 0.05 vs vehicle control, n = 6 per group).

Table S1. Original data of all the 655 probes in cortex of normoxic control and HPC mice (n = 12 per group)

Table S2. Original data of all the 655 probes in cortex of the sham control and peri-infarct region of 6 h MCAO mice (n = 12 per group)

Table S3. Original data of all the 655 probes in peri-infarct region of 6 h MCAO (I) and HPC+I mice (n = 12 per group)

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