Figure S1. Histological staining with H&E on normal brain tissue (a), non-tumor brain tissue control (b), low-grade glioma tissue (c) and high-grade glioma tissue (d).

Figure S2. The levels of anandamide (a), 2-AG (b), and OEA (c) in normal brain tissues (open bars) and non-tumor brain tissues (closed bars).

Figure S3. Immuno-histochemistry showed the increase of CB1 in human gliomas. The expression level of CB1 was detected with antibody against CB1 in non-tumor brain tissues (a), low-grade gliomas (b), and high-grade gliomas (c).

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