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Appendix S1. Supplementary materials and methods.

Table S1. Cohort Demographics.

Figure S1. Validating the effect of different structural forms of Aβ42 on alternative exon splicing of a TrkB minigene expressed in differentiated SHSY5Y cells.

Figure S2. Srp20 and hnrnpK mRNA expression in AD.

Figure S3. Temporal cortex Srp20 and hnrnpK mRNA expression in AD.

Figure S4. Polypyrimidine tract of TrkB exon 19 acceptor site.

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