Srp20 regulates TrkB pre-mRNA splicing to generate TrkB-Shc transcripts with implications for Alzheimer’s disease
Version of Record online: 16 AUG 2012
© 2012 The Authors. Journal of Neurochemistry © 2012 International Society for Neurochemistry
Journal of Neurochemistry
Volume 123, Issue 1, pages 159–171, October 2012
How to Cite
Wong, J., Garner, B., Halliday, G. M. and Kwok, J. B. J. (2012), Srp20 regulates TrkB pre-mRNA splicing to generate TrkB-Shc transcripts with implications for Alzheimer’s disease. Journal of Neurochemistry, 123: 159–171. doi: 10.1111/j.1471-4159.2012.07873.x
- Issue online: 10 SEP 2012
- Version of Record online: 16 AUG 2012
- Accepted manuscript online: 12 JUL 2012 12:25PM EST
- Received June 6, 2012; revised manuscript received July 9, 2012; accepted July 10, 2012.
Appendix S1. Supplementary materials and methods.
Table S1. Cohort Demographics.
Figure S1. Validating the effect of different structural forms of Aβ42 on alternative exon splicing of a TrkB minigene expressed in differentiated SHSY5Y cells.
Figure S2. Srp20 and hnrnpK mRNA expression in AD.
Figure S3. Temporal cortex Srp20 and hnrnpK mRNA expression in AD.
Figure S4. Polypyrimidine tract of TrkB exon 19 acceptor site.
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