Two hundred married professional women with small children were surveyed to investigate what types of occupational and role-conflict stresses are associated with physical and depressive symptoms, and whether social support could protect individuals from the negative health effects of stress. Six stress indices predicted physical and depressive symptoms, both Concurrently and 1 year later. These stresses reflected perceptions of lack of authority and influence on the job, sex discrimination, a heavy work load, work imposing on relaxation, family imposing on relaxation, and overall suffering from role conflict. Social support yielded no stress-buffering effects.