hybridlab (version 1.0): a program for generating simulated hybrids from population samples

  1. EINAR EG NIELSEN1,
  2. LARS ARVE BACH2,
  3. PIOTR KOTLICKI3

Article first published online: 20 JUL 2006

DOI: 10.1111/j.1471-8286.2006.01433.x

Issue

Molecular Ecology Notes

Molecular Ecology Notes

Volume 6, Issue 4, pages 971–973, December 2006

Additional Information

How to Cite

NIELSEN, E. E., BACH, L. A. and KOTLICKI, P. (2006), hybridlab (version 1.0): a program for generating simulated hybrids from population samples. Molecular Ecology Notes, 6: 971–973. doi: 10.1111/j.1471-8286.2006.01433.x

Author Information

  1. 1

    Department of Inland Fisheries, Danish Institute for Fisheries Research, DK-8600 Silkeborg, Denmark,

  2. 2

    Department of Theoretical Ecology, Sölvegatan 37 Ecology Building, Lund University, SE-223 62 Sweden,

  3. 3

    Department of Computer Science, University of Aarhus, IT-parken, Aabogade 34, DK-8200 Aarhus N, Denmark

* E.E. Nielsen. Fax: +4589213150; E-mail: een@difres.dk

Publication History

  1. Issue published online: 20 JUL 2006
  2. Article first published online: 20 JUL 2006
  3. Received 18 February 2006; revision received 25 March 2006; accepted 12 April 2006

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Keywords:

  • assignment tests;
  • computer program;
  • hybridization;
  • nuclear markers;
  • simulation

Abstract

We present the computer program hybridlab 1.0 for simulating intraspecific hybrids from population samples of nuclear genetic markers such as microsatellites, allozymes or SNPs (single nucleotide polymorphisms). The program generates a user-specified number of multilocus F1 hybrid genotypes between any pair of potentially hybridizing populations included in a standard input-file of multilocus genotypes for population genetic analysis. This simple, user-friendly program has a wide range of applications for studying natural and artificial hybridization; in particular, for evaluating the statistical power for individual assignment of parental and hybrid individuals. An example of application for Atlantic cod populations is given.

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