Trichophyton species susceptibility to green and red propolis from Brazil
Article first published online: 19 NOV 2008
© 2008 The Authors. Journal compilation © 2008 The Society for Applied Microbiology
Letters in Applied Microbiology
Volume 48, Issue 1, pages 90–96, January 2009
How to Cite
Siqueira, A.B.S., Gomes, B.S., Cambuim, I., Maia, R., Abreu, S., Souza-Motta, C.M., De Queiroz, L.A. and Porto, A.L.F. (2009), Trichophyton species susceptibility to green and red propolis from Brazil. Letters in Applied Microbiology, 48: 90–96. doi: 10.1111/j.1472-765X.2008.02494.x
- Issue published online: 6 JAN 2009
- Article first published online: 19 NOV 2008
- 2008/1198: received 11 July 2008, revised 9 September 2008 and accepted 10 September 2008
- Brazilian green propolis;
- Brazilian red propolis;
- Trichophyton sp
Aims: The in vitro antifungal activity of Brazilian green and red propolis was tested against different species of Trichophyton.
Methods and Results: The antifungal activity of the Brazilian aqueous and alcoholic extracts of the green propolis and the alcoholic extract of red propolis was observed against Trichophyton rubrum, Trichophyton tonsurans and Trichophyton mentagrohytes samples, using as controls itraconazole and terbinafine. The minimal inhibitory concentration was determined following the microdilution method indicated by the ‘Clinical and Laboratory Standards Institute’. The minimal fungicide concentration was determined by the absence of growth in liquid sabouraud culture medium. The data obtained showed that the green propolis alcoholic extract’s antifungal activity was from 64 to 1024 μg ml−1, whereas the red propolis alcoholic extract was from 8 to 1024 μg ml−1.
Conclusions: The antifungal activity of the red propolis alcoholic extract was more efficient than the green propolis alcoholic extract for all three species studied. The T. rubrum samples were shown to be more sensitive to the antifungal activity of the alcoholic extracts of the propolis.
Significance and Impact of the Study: The antifungal potential of the alcoholic extracts of green and red propolis demonstrated suggest an applicable potential as an alternative treatment for dermatophytosis caused by these species.