Virucidal efficacy of povidone-iodine-containing disinfectants
Article first published online: 14 MAY 2010
© 2010 The Authors. Journal compilation © 2010 The Society for Applied Microbiology
Letters in Applied Microbiology
Volume 51, Issue 2, pages 158–163, August 2010
How to Cite
Sauerbrei, A. and Wutzler, P. (2010), Virucidal efficacy of povidone-iodine-containing disinfectants. Letters in Applied Microbiology, 51: 158–163. doi: 10.1111/j.1472-765X.2010.02871.x
- Issue published online: 9 JUL 2010
- Article first published online: 14 MAY 2010
- 2010/0669: received 22 April 2010, revised 5 May 2010 and accepted 6 May 2010
- Betaseptic Mundipharma®;
- German guideline for virucidal testing of biocides;
- virucidal efficacy
Aims: The objective of this study was to evaluate virucidal efficacy of the commercially available povidone-iodine formulations Betaisodona® solution and Betaseptic Mundipharma® (Mundipharma).
Methods and Results: The quantitative suspension test for virucidal testing of biocides according to the German guideline was used as method. The use of Betaisodona® solution resulted in virucidal efficacy, corresponding to ≥104-fold reduction in viral titre, against vaccinia virus, bovine viral diarrhoea virus and polyomavirus SV40 within 0·5 min and adenovirus type 5 within 3–5 min without and with organic load. For inactivation of the most resistant poliovirus type 1, a time interval of ≥60 min was needed. By contrast, Betaseptic Mundipharma® inactivated significantly all model viruses for virucidal testing including poliovirus type 1 within 5 min independently from the addition of proteins.
Conclusions: Betaisodona® solution shows a good efficacy against enveloped model viruses as well as against some nonenveloped human viruses, e.g. adenovirus and polyomavirus. Betaseptic Mundipharma® has an excellent virucidal efficacy including the inactivation of the most resistent poliovirus type 1.
Significance and Impact of the Study: The findings of this study make Betaseptic Mundipharma® suitable for virucidal disinfection of the skin within short time intervals.