The cosmetic treatment of wrinkles
Article first published online: 15 NOV 2004
DOI: 10.1111/j.1473-2130.2004.00054.x
Additional Information
How to Cite
Rona, C., Vailati, F. and Berardesca, E. (2004), The cosmetic treatment of wrinkles. Journal of Cosmetic Dermatology, 3: 26–34. doi: 10.1111/j.1473-2130.2004.00054.x
Publication History
- Issue published online: 15 NOV 2004
- Article first published online: 15 NOV 2004
- Accepted for publication 09 July 2004
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Keywords:
- AHAs;
- antioxidants;
- fish cartilage;
- pycnogenol;
- retinoids;
- skin ageing;
- wrinkles
Summary
Wrinkles now have a greater social impact because people live longer. Science and hedonism overlap in the search for causes, treatments and prevention of wrinkles.
The cosmetic approach to wrinkles includes:
- i Cleansing
- ii Photoprotection
- iii Active ingredients
Active ingredients go well beyond simple moisturisers and exert a more complex activity in protecting skin from external injuries, nourishing it and removing its superficial layers. Transport systems and excipients are increasingly effective. Functional agents currently include alpha hydroxy acids (AHAs), poly-AHAs, complex poly-AHAs, retinoids, fish polysaccharides, anti-enzymatic agents, antioxidants (including ascorbic acid, pycnogenol, ursolic acid, vegetable isoflavones, vitamin E, coenzyme Q10, lipoic acid, resveratorol, l-carnosine and taurine) as well as agaricic acid and various plant extracts. All are reviewed in this text. Most are topical, some can be given by mouth, even as food supplements.
Cosmetics are becoming closer to drugs in preventing and treating wrinkles. Included amongst the cosmeceuticals are the anti-wrinkle agents described herein.

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