Development and evaluation of polyherbal formulation for hair growth–promoting activity
Article first published online: 22 MAY 2007
Journal of Cosmetic Dermatology
Volume 6, Issue 2, pages 108–112, June 2007
How to Cite
Roy, R. K., Thakur, M. and Dixit, V. K. (2007), Development and evaluation of polyherbal formulation for hair growth–promoting activity. Journal of Cosmetic Dermatology, 6: 108–112. doi: 10.1111/j.1473-2165.2007.00305.x
- Issue published online: 22 MAY 2007
- Article first published online: 22 MAY 2007
- Accepted for publication November 6, 2006
- Citrullus colocynthis;
- Cuscuta reflexa;
- Eclipta alba;
- hair growth
Background Cuscuta reflexa (Roxb.), Citrullus colocynthis (Schrad.), and Eclipta alba (Hassk.) are traditionally acclaimed herbs for their hair growth–promoting potential.
Aim In the present study, it was envisaged to prepare herbal formulations containing petroleum ether extracts of the three herbs in varying ratio and evaluating the formulations for the hair growth–promoting activity.
Methods The formulations as well as minoxidil (2%) solution (positive control) were applied topically on shaved skin of rats, and the time required for initiation and completion of hair growth cycle was recorded.
Results and conclusions Hair growth initiation time was markedly reduced to one third on treatment with the prepared formulation compared with control animals. The time required for complete hair growth was also reduced by 32%. Quantitative analysis of hair growth cycle after treatment with formulations and minoxidil (2%) exhibited greater number of hair follicles in anagenic phase compared with control. The results thus corroborate with the traditionally acclaimed hair growth–promoting capabilities of the plants. The prepared formulation also holds potential for treatment of alopecia.