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Bioactive peptides: signaling the future
Article first published online: 17 FEB 2009
DOI: 10.1111/j.1473-2165.2009.00416.x
© 2009 Wiley Periodicals, Inc
Additional Information
How to Cite
Fields, K., Falla, T. J., Rodan, K. and Bush, L. (2009), Bioactive peptides: signaling the future. Journal of Cosmetic Dermatology, 8: 8–13. doi: 10.1111/j.1473-2165.2009.00416.x
Publication History
- Issue published online: 17 FEB 2009
- Article first published online: 17 FEB 2009
- Accepted for publication September 26, 2008
- Abstract
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Keywords:
- bioactive peptides;
- active ingredient;
- acne;
- antiaging;
- anti-inflammatory and wound healing
Summary
Natural processes within the body are modulated almost exclusively by the interaction of specific amino acid sequences, either as peptides or as subsections of proteins. With respect to skin, proteins and peptides are involved in the modulation of cell proliferation, cell migration, inflammation, angiogenesis, melanogenesis, and protein synthesis and regulation. The creation of therapeutic or bioactive peptide analogs of specific interactive sequences has opened the door to a diverse new field of pharmaceutical and active cosmetic ingredients for the skincare industry. Here, we describe the origin of such sequences, their role in nature, their application to dermatology, as well as the advantages and challenges posed by this new technology.