SEARCH

SEARCH BY CITATION

References

  • Bilousova G, Marusyk A, Porter CC, Cardiff RD, DeGregori J (2005) Impaired DNA replication within progenitor cell pools promotes leukemogenesis. PLoS Biol. 3, e401.
  • Garcia-Cao I, Garcia-Cao M, Martin-Caballero J, Criado LM, Klatt P, Flores JM, Weill JC, Blasco MA, Serrano M (2002) ‘Super p53’ mice exhibit enhanced DNA damage response, are tumor resistant and age normally. EMBO J. 21, 62256235.
  • Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100, 5770.
  • Janzen V, Forkert R, Fleming H, Saito Y, Waring MT, Dombkowski DM, Cheng T, DePinho RA, Sharpless NE, Scadden DT (2006) Stem cell aging modified by the cyclin-dependent kinase inhibitor, p16INK4a. Nature 443, 421426.
  • Krishnamurthy J, Ramsey MR, Ligon KL, Torrice C, Koh A, Bonner-Weir S, Sharpless NE (2006) p16INK4a induces an age-dependent decline in islet regenerative potential. Nature 443, 453457.
  • Maier B, Gluba W, Bernier B, Turner T, Mohammad K, Guise T, Sutherland A, Thorner M, Scrable H (2004) Modulation of mammalian life span by the short isoform of p53. Genes Dev. 18, 306319.
  • Matheu A, Pantoja C, Efeyan A, Criado LM, Martin-Caballero J, Flores JM, Klatt P, Serrano M (2004) Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging. Genes Dev. 18, 27362746.
  • Mendrysa SM, O’leary KA, McElwee MK, Michalowski J, Eisenman RN, Powell DA, Perry ME (2006) Tumor suppression and normal aging in mice with constitutively high p53 activity. Genes Dev 20, 1621.
  • Molofsky AV, Slutsky SG, Joseph NM, He S, Pardal R, Krishnamurthy J, Sharpless NE, Morrison SJ (2006) Declines in forebrain progenitor function and neurogenesis during aging are partially caused by increasing Ink4a expression. Nature 443, 448452.
  • Reed MJ, Edelberg JM (2004) Impaired angiogenesis in the aged. Sci Aging Knowl. Environ. 2004, pe7.
  • Reed MJ, Karres N, Eyman D, Cruz A, Brekken RA, Plymate S (2007) The effects of aging on tumor growth and angiogenesis are tumor-cell dependent. Int. J. Cancer 120, 753760.
  • Tyner SD, Venkatachalam S, Choi J, Jones S, Ghebranious N, Ingelmann H, Lu X, Soron G, Cooper B, Brayton C, Park SH, Thompson T, Karsenty G, Bradley A, Donehower LA (2002) p53 mutant mice that display early aging-associated phenotypes. Nature 415, 4553.