• Open Access

Protein translation, 2007


Matt Kaeberlein, Department of Pathology, University of Washington, Box 357470, Seattle, WA 98195-7470, USA. Tel.: (206) 543 4849; fax: (206) 543 3644; e-mail: kaeber@u.washington.edu
Brian K. Kennedy, Department of Biochemistry, University of Washington, Box 357350, Seattle, WA 98195-7350, USA. Tel.: (206) 685 0111; fax: (206) 685 1792; e-mail: bkenn@u.washington.edu


Translation of RNA to protein is essential for life. It should perhaps not be surprising, therefore, that appropriate regulation of translation plays a key role in determining longevity. This Hot Topic article discusses papers published in the last year related to the importance of translation and its regulation by signaling through the target of rapamycin kinase, in modulating aging and age-associated diseases.