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  • Bartke A, Wright JC, Mattison JA, Ingram DK, Miller RA, Roth GS (2001) Extending the lifespan of long-lived mice. Nature 414, 412.
  • Berry A, Capone F, Giorgio M, Pelicci PG, De Kloet ER, Alleva E, Minghetti L, Cirulli F (2007) Deletion of the life span determinant p66Shc prevents age-dependent increases in emotionality and pain sensitivity in mice. Exp. Gerontol. 42, 3745.
  • Berry A, Greco A, Giorgio M, Pelicci PG, De Kloet R, Alleva E, Minghetti L, Cirulli F (2008) Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice. Exp. Gerontol. 43, 200–208.
  • Blüher M, Kahn BB, Kahn CR (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299, 572574.
  • Bonkowski MS, Rocha JS, Masternak MM, Al Regaiey KA, Bartke A (2006) Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proc. Natl Acad. Sci. USA 16, 103.
  • Brown-Borg HM, Borg KE, Meliska CJ, Bartke A (1996) Dwarf mice and the aging process. Nature 384, 33.
  • Conover CS, Bale LK (2007) Loss of pregnancy-associated plasma protein A extends lifespan in mice. Aging Cell 6, 727729.
  • Conti B, Sanchez-Alavez M, Winsky-Sommerer R, Morale MC, Lucero J, Brownell S, Fabre V, Huitron-Resendiz S, Henriksen S, Zorrilla EP, De Lecea L, Bartfai T (2006) Transgenic mice with a reduced core body temperature have an increased life span. Science 314, 825828.
  • Coschigano KT, Clemmons D, Bellush LL, Kopchick JJ (2000) Assessment of growth parameters and lifespan of GHR/BP gene-disrupted mice. Endocrinology 141, 26082613.
  • Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A, Kopchick JJ (2003) Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology 144, 37993810.
  • Cosentino F, Francia P, Camici GG, Pelicci PG, Lüscher TF (2008) Final common molecular pathways of aging and cardiovascular disease. Role of the p66Shc protein. Arterioscler. Thromb. Vasc. Biol. 28, 622–628.
  • Dell’Agnello C, Leo S, Agostino A, Szabadkai G, Tiveron C, Zulian A, Prelle A, Roubertoux P, Rizzuto R, Zeviani M (2007) Increased longevity and refractoriness to Ca2+-dependent neurodegeneration in Surf1 knockout mice. Hum. Mol. Genet. 16, 431444.
  • Flurkey K, Papaconstantinou J, Miller RA, Harrison DE (2001) Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production. Proc. Natl Acad. Sci. USA 98, 67366741.
  • Flurkey K, Papaconstantinou J, Harrison DE (2002) The Snell dwarf mutation Pit1(dw) can increase lifespan in mice. Mech. Ageing Dev. 123, 121130.
  • Guarente L, Kenyon C (2000) Genetic pathways that regulate ageing in model organisms. Nature 408, 255262.
  • Hakimi P, Yang J, Casadesus G, Massillon D, Tolentino-Silva F, Nye CK, Cabrera ME, Hagen DR, Utter CB, Baghdy Y, Johnson DH, Wilson DL, Kirwan JP, Kalhan SC, Hanson RW (2007) Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse. J. Biol. Chem. 282, 3284432855.
  • Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC, Cervera P, Le Bouc Y (2003) IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421, 182187.
  • Ikeno Y, Bronson RT, Hubbard GB, Lee S, Bartke A (2003) Delayed occurrence of fatal neoplastic diseases in Ames dwarf mice: correlation to extended longevity. J. Gerontol. A Biol. Sci. Med. Sci. 58, 291296.
  • Ikeno Y, Hubbard GB, Lee S, Cortez LA, Lew CM, Webb CR, Berryman DE, List EO, Kopchick JJ, Bartke A (2009) Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/binding protein knockout mice. J. Gerontol. A Biol. Sci. Med. Sci. 64, 522529.
  • Johnson TE, Henderson S, Murakami S, De Castro E, De Castro SH, Cypser J, Rikke B, Tedesco P, Link C (2002) Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease. J. Inherit. Metab. Dis. 25, 197206.
  • Kinney BA, Meliska CJ, Steger RW, Bartke A (2001a) Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters. Horm. Behav. 39, 277284.
  • Kinney BA, Coschigano KT, Kopchick JJ, Steger RW, Bartke A (2001b) Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice. Physiol. Behav. 72, 653660.
  • Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M (2005) Suppression of aging in mice by the hormone Klotho. Science 309, 18291833.
  • Li Q, Ren J (2007) Influence of cardiac-specific overexpression of insulin-like growth factor 1 on lifespan and aging-associated changes in cardiac intracellular Ca2+ homeostasis, protein damage and apoptotic protein expression. Aging Cell 6, 799806.
  • Liang H, Masoro EJ, Nelson JF, Strong R, McMahan CA, Richardson A (2003) Genetic mouse models of extended life span. Exp. Gerontol. 38, 13531364.
  • Lithgow GJ (1996) Invertebrate gerontology: the age mutations of Caenorhabditis elegans. BioEssays 18, 809815.
  • De Magalhães JP, Cabral JA, Magalhães D (2005) The influence of genes on the aging process of mice: a statistical assessment of the genetics of aging. Genetics 169, 265274. Epub 2004 Sep 30.
  • Masoro EJ (1993) Dietary restriction and aging. J. Am. Geriatr. Soc. 41, 994999.
  • Masoro EJ (2002) Caloric Restriction: A Key to Understanding and Modulating Aging. Amsterdam: Elsevier Science.
  • McCarter R, Mejia W, Ikeno Y, Monnier V, Kewitt K, Gibbs M, McMahan A, Strong R (2007) Plasma glucose and the action of calorie restriction on aging. J. Gerontol. A Biol. Sci. Med. Sci. 62, 10591070.
  • Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, Pandolfi PP, Lanfrancone L, Pelicci PG (1999) The p66shc adaptor protein controls oxidative stress response and lifespan in mammals. Nature 402, 309313.
  • Miskin R, Masos T (1997) Transgenic mice overexpressing urokinase-type plasminogen activator in the brain exhibit reduced food consumption, body weight and size, and increased longevity. J. Gerontol. 52, B18B24.
  • Partridge L, Gems D (2002) Mechanisms of ageing: public or private? Nat. Genet. 3, 165178.
  • Petkov PM, Ding Y, Cassell MA, Zhang W, Wagner G, Sargent EE, Asquith S, Crew V, Johnson KA, Robinson P, Scott VE, Wiles MV (2004) An efficient SNP system for mouse genome scanning and elucidating strain relationships. Genome Res. 14, 18061811.
  • Phelan JP, Austad SN (1994) Selecting animal models of human aging: inbred strains often exhibit less biological uniformity than F1 hybrids. J. Gerontol. 49, B1B11.
  • Pinton P, Rimessi A, Marchi S, Orsini F, Migliaccio E, Giorgio M, Contursi C, Minucci S, Mantovani F, Wieckowski MR, Del Sal G, Pelicci PG, Rizzuto R (2007) Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc. Science 2 315, 659663.
  • Redden DT, Fernández JR, Allison DB (2004) A simple significance test for quantile regression. Stat. Med. 23, 25872597.
  • Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Emond M, Coskun PE, Ladiges W, Wolf N, Van Remmen H, Wallace DC, Rabinovitch PS (2005) Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308, 19091911.
  • Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson ICA, Thornton JM, Gems D, Partridge L, Withers DJ (2008) Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB J. 22, 807817.
  • Shimokawa I, Yu BP, Higami Y, Ikeda T, Masoro EJ (1993) DR retards onset but not progression of leukemia in male F344 rats. J. Gerontol. 48, B68B73.
  • Smith GS, Walford RL, Mickey MR (1973) Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F1 hybrids. J. Natl Cancer Inst. 50, 11951213.
  • Storer JB (1966) Longevity and gross pathology at death in 22 inbred strains of mice. J. Gerontol. 21, 404409.
  • Taguchi A, Wartschow LM, White MF (2007) Brain IRS2 Signaling Coordinates Life Span and Nutrient Homeostasis. Science 317, 369372.
  • Treuting PM, Linford NJ, Knoblaugh SE, Emond MJ, Morton JF, Martin GM, Rabinovitch PS, Ladiges WC (2008) Reduction of age-associated pathology in old mice by overexpression of catalase in mitochondria. J. Gerontol. Biol. Sci. 63, 813822.
  • Turturro A, Witt WW, Lewis S, Hass BS, Lipman RD, Hart RW (1999) Growth curves and survival characteristics of the animals used in the biomarkers of aging. Program. J. Gerontol. A Biol. Sci. Med. Sci. 54, B492B501.
  • Vergara M, Smith-Wheelock M, Harper JM, Sigler R, Miller RA (2004) Hormone-treated snell dwarf mice regain fertility but remain long lived and disease resistant. J. Gerontol. A Biol. Sci. Med. Sci. 59, 12441250.
  • Wang C, Li Q, Redden DT, Weindruch R, Allison DB (2004) Statistical methods for testing effects on “maximum lifespan”. Mech. Ageing Dev. 125, 629632.
  • Ware C, Siverts L, Nelson A, Morton J, Ladiges W (2003) Utility of a C57BL/6 ES cell line versus 129 ES cell lines for targeted mutations in mice. Transgenics 12, 743746.
  • Weindruch R, Walford RL (1988) The Retardation of Aging and Disease by Dietary Restriction. Springfield, IL: Thomas.
  • Witten TM, Bonchev D (2007) Predicting aging/longevity-related genes in the nematode Caenorhabditis elegans. Chem. Biodivers. 4, 26392655.
  • Yan L, Vatner DE, O’Connor JP, Ivessa A, Ge H, Chen W, Hirotani S, Ishikawa Y, Sadoshima J, Vatner SF (2007) Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell 130, 247258.
  • Yang S, Doser TA, Fang CX, Nunn JM, Janardhanan R, Zhu M, Sreejayan N, Quinn MT, Ren J (2006) Metallothionein prolongs survival and antagonizes senescence-associated cardiomyocyte diastolic dysfunction: role of oxidative stress. FASEB J. 20, 10241102.
  • Yen K, Steinsaltz D, Mobbs CV (2008) Validated analysis of mortality rates demonstrates distinct genetic mechanisms that influence lifespan. Exp. Gerontol. 43, 10441051. Epub 2008 Sep 14.