Age-related changes in mesenchymal stem cells derived from rhesus macaque bone marrow
Article first published online: 12 JAN 2011
© 2011 The Authors. Aging Cell © 2011 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland
Volume 10, Issue 1, pages 66–79, February 2011
How to Cite
Yu, J. M., Wu, X., Gimble, J. M., Guan, X., Freitas, M. A. and Bunnell, B. A. (2011), Age-related changes in mesenchymal stem cells derived from rhesus macaque bone marrow. Aging Cell, 10: 66–79. doi: 10.1111/j.1474-9726.2010.00646.x
- Issue published online: 12 JAN 2011
- Article first published online: 12 JAN 2011
- Accepted manuscript online: 22 OCT 2010 02:25PM EST
- Accepted for publication 29 September 2010
Fig. S1 Morphological appearance of rBMSCs in three age groups (A) shows cell morphology at the first passage from young rBMSCs (< 5 years), middle rBMSCs (8-10 years), and old rBMSCs (> 12 years), respectively. Original magnification, 10×. (B) rBMSCs obtained from three age groups were analyzed for cell size. Shown is a representative single-parameter histogram. (C) A representative flow cytometry plot of rBMSCs in three age groups according to light scatter characteristics reflecting cytoplasmic granularity and cell size.
Fig. S2 HPLC separation of histones from rBMSCs cells in young and old group. (A) All core histones are observed. (B) Several variants of histone H2B, H2A, H3 and H4 were separated and their retention times were labeled on the top of their corresponding peaks.
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