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Fig. S1 Scattergrams showing the correlations of fat in AL and DR mice measured at 15–17 and 20–22 months of age.

Fig. S2 Scattergram showing the correlations of lean in AL and DR mice measured at 15–17 and 20–22 months of age.

Fig. S3 Strain variation in body weight (BW) of ILSXISS recombinant inbred (RI) mice aged 15–17 months under ad libitum (AL) and 40% dietary restriction (DR) diets.

Fig. S4 Quantitative trait loci (QTL) mapping for lifespan in females under ad libitum (AL).

Fig. S5 Strain variation in % fat mass of ILSXISS recombinant inbred (RI) mice aged 15–17 months under ad libitum (AL) and 40% dietary restriction (DR) diets.

Table S1 Relationships of lifespan, fat mass, lean mass, and body weight (BW) at 15–17 months of age between ad libitum (AL) and 40% dietary restriction (DR) feedings.

Table S2 Relationships between males and females of lifespan, fat mass, lean mass, and body weight (BW) at 15–17 months of age under ad libitum (AL) and 40% dietary restriction (DR) feedings.

Table S3 Correlation coefficients among strain means between absolute fat mass, lean mass, and body weight (BW) at 15–17 months of age with mean lifespan in both sexes and diets.

Table S4 Correlation coefficients among strain means between absolute fat mass, lean mass, and body weight (BW) at 20–22 months of age with mean lifespan in both sexes and diets.

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