Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics)

  1. Tomoaki Uchiki1,†,
  2. Karen A. Weikel1,†,
  3. Wangwang Jiao1,†,‡,
  4. Fu Shang1,†,
  5. Andrea Caceres1,
  6. Dorota Pawlak2,
  7. James T. Handa3,
  8. Michael Brownlee4,
  9. Ram Nagaraj5,
  10. Allen Taylor1

Article first published online: 15 NOV 2011

DOI: 10.1111/j.1474-9726.2011.00752.x

Issue

Aging Cell

Aging Cell

Volume 11, Issue 1, pages 1–13, February 2012

Additional Information

How to Cite

Uchiki, T., Weikel, K. A., Jiao, W., Shang, F., Caceres, A., Pawlak, D., Handa, J. T., Brownlee, M., Nagaraj, R. and Taylor, A. (2012), Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics). Aging Cell, 11: 1–13. doi: 10.1111/j.1474-9726.2011.00752.x

Author Information

  1. 1

    Laboratory for Nutrition and Vision Research, USDA Human Nutrition Research Center on Aging, Tufts University 711 Washington St, Boston, MA 02111, USA

  2. 2

    Harvard Medical School, Children’s Hospital Boston, 300 Longwood Avenue Boston, MA, 02115, USA

  3. 3

    Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA

  4. 4

    Department of Medicine, Albert Einstein College of Medicine, Forchheimer Building, Room 531, 1300 Morris Park Av, Bronx, NY 10461, USA

  5. 5

    Department of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, OH 44106, USA

  1. †

    Equal contributors to this work.

  2. ‡

    Deceased. This paper is dedicated to the pioneering work of Wangwang Jiao, the talented young fellow who began this work, but was not allowed to live to see it to fruition.

* Allen Taylor, Laboratory for Nutrition and Vision Research, USDA Human Nutrition Research Center on Aging, Tufts University 711 Washington St, Boston, MA 02111, USA. Tel.: 617 556 3155; fax: 617 556 3132; e-mail: allen.taylor@tufts.edu

  1. †

    Equal contributors to this work.

  2. ‡

    Deceased. This paper is dedicated to the pioneering work of Wangwang Jiao, the talented young fellow who began this work, but was not allowed to live to see it to fruition.

Publication History

  1. Issue published online: 12 JAN 2012
  2. Article first published online: 15 NOV 2011
  3. Accepted manuscript online: 3 OCT 2011 12:23PM EST
  4. Accepted for publication 16 September 2011

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