Present address: Department of Pathology and Laboratory Medicine, School of Medicine, Boston University, Boston, MA 02118, USA.
Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans
Article first published online: 19 JAN 2012
© 2011 The Authors. Aging Cell © 2011 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland
Volume 11, Issue 2, pages 315–325, April 2012
How to Cite
Ni, Z., Ebata, A., Alipanahiramandi, E. and Lee, S. S. (2012), Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegans. Aging Cell, 11: 315–325. doi: 10.1111/j.1474-9726.2011.00785.x
- Issue published online: 15 MAR 2012
- Article first published online: 19 JAN 2012
- Accepted manuscript online: 29 DEC 2011 12:59PM EST
- Accepted for publication 18 December 2011
Fig. S1 SET-26 is expressed in both germline and somatic tissues.
Fig. S2 set-9 and set-26 have redundant functions in affecting worm lifespan.
Fig. S3 set-26(tm2467) mutation partially depends on daf-16 to extend glp-1(e2141) worm lifespan, but does not affect daf-16 RNA level.
Fig. S4 set-26(tm2467) mutation affects the expression of some of the known DAF-16 target genes.
Table S1 Lifespan screen of 50 RNAi clones in wild type worms targeting putative histone methyltransferase and demethylase genes.
Table S2 Lifespan data for the figures and supplementary figures.
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