Fig. S1 A representative experiment showing Genescan electropherogram patterns obtained from DNAs with different degree of skewing and a male DNA used as negative control.

Table S1 List of 28 CpGs resulted significantly (q-value < 0.05) hypermethylated and hypomethylated in centenarians’offspring compared with offspring of non long-lived parents . q-values has been calculated vs Centenarians' Offspring group.

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