Age-dependent skewing of X chromosome inactivation appears delayed in centenarians’ offspring. Is there a role for allelic imbalance in Healthy Aging and Longevity?
Article first published online: 1 FEB 2012
© 2011 The Authors. Aging Cell © 2011 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland
Volume 11, Issue 2, pages 277–283, April 2012
How to Cite
Gentilini, D., Castaldi, D., Mari, D., Monti, D., Franceschi, C., Di Blasio, A. M. and Vitale, G. (2012), Age-dependent skewing of X chromosome inactivation appears delayed in centenarians’ offspring. Is there a role for allelic imbalance in Healthy Aging and Longevity?. Aging Cell, 11: 277–283. doi: 10.1111/j.1474-9726.2012.00790.x
- Issue published online: 15 MAR 2012
- Article first published online: 1 FEB 2012
- Accepted for publication 5 December 2011
Fig. S1 A representative experiment showing Genescan electropherogram patterns obtained from DNAs with different degree of skewing and a male DNA used as negative control.
Table S1 List of 28 CpGs resulted significantly (q-value < 0.05) hypermethylated and hypomethylated in centenarians’offspring compared with offspring of non long-lived parents . q-values has been calculated vs Centenarians' Offspring group.
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